Enzyme-linked immunosorbent assay to determine the potency of a rotavirus vaccine based on virus-like particles: analytical procedure development and validation

Enzyme-linked immunosorbent assay to determine the potency of a rotavirus vaccine based on virus-like particles: analytical procedure development and validation

INTRODUCTION. Rotavirus vaccines based on virus-like particles (VLPs), non-infectious recombinant proteins of human rotavirus A that mimic the structure of the native virus, show promise for preventive vaccination. Presumably, the optimal method to determine the potency of VLP-based rotavirus vaccin...

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Bibliographic Details
Main Authors: I. E. Filatov, M. M. Silaenkova, V. V. Tsibezov, M. V. Balandina, S. N. Norkina, O. E. Latyshev, O. V. Eliseeva, S. A. Cherepushkin, T. V. Grebennikova
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-12-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
human rotavirus a
virus-like particles
vlp
rotavirus vaccine
potency
enzyme-linked immunosorbent assay
virus neutralisation test
validation
<i>in vivo</i>
Online Access:https://www.biopreparations.ru/jour/article/view/595
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