A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria.
Infertility remains a very common global issue that is often associated with several factors such as hormonal, cervical, uterine, immunological or psychological influences. Aside from these factors, there are instances where infertility remains inexplicable. Therefore, further research is required t...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hammer Head Production Limited
2025-05-01
|
| Series: | Sokoto Journal of Medical Laboratory Science |
| Subjects: | |
| Online Access: | https://sokjmls.com.ng/index.php/SJMLS/article/view/657 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850184343202299904 |
|---|---|
| author | Onitsha, Enebrayi Nelson1*, Okutu Jackson Borobuebi1; Ebizuoye Stow Francis1; Lokoja Ebiweni James1; Ezeiruaku Ferdinand Chukwuma 1; Iniwarikenimi Ebipadei Jeremiah 1; and Oviri Blessing 2 |
| author_facet | Onitsha, Enebrayi Nelson1*, Okutu Jackson Borobuebi1; Ebizuoye Stow Francis1; Lokoja Ebiweni James1; Ezeiruaku Ferdinand Chukwuma 1; Iniwarikenimi Ebipadei Jeremiah 1; and Oviri Blessing 2 |
| author_sort | Onitsha, Enebrayi Nelson1*, Okutu Jackson Borobuebi1; Ebizuoye Stow Francis1; Lokoja Ebiweni James1; Ezeiruaku Ferdinand Chukwuma 1; Iniwarikenimi Ebipadei Jeremiah 1; and Oviri Blessing 2 |
| collection | DOAJ |
| description | Infertility remains a very common global issue that is often associated with several factors such as hormonal, cervical, uterine, immunological or psychological influences. Aside from these factors, there are instances where infertility remains inexplicable. Therefore, further research is required to identify the underlying causes of unexplained infertility. This study assessed the nexus between blood groups and male infertility by evaluating the serum testosterone levels. The study utilized a cross-sectional study design. A total of 200 male within the ages of 18 to 40 years attending fertility clinic at the Federal Medical Centre Yenagoa, Family Care Hospital, Yenagoa, and Tobis Clinic and Consultant between the period of February 2023 and August 2024 were recruited for the study. The subjects consist of 120 known infertile male patients, and 60 apparently healthy fertile males, which served as the control group. Five milliliters of blood was collected following standard procedures and used for the determination of blood groups and testosterone levels using Slide Haem-agglutination technique and Enzyme linked immunosorbent assay (ELISA) technique respectively. Special Package for Social Science version 23.0 was used to perform the statistical analysis, and p-value less than 0.05 was considered statistically significant. The result revealed that the distribution of blood groups in the studied population was 61.7%, 21.7%, 11.7%, and 5.0% for blood groups O, B, A and AB respectively. The Rhesus blood group distribution in the infertile males was 95.0% and 5.0% for Rhesus D positive and negative respectively. The mean values of testosterone in blood group O males were slightly higher than group A, AB and B, but not statistically significant (p>0 . 05) . Furthermore, the mean values of testosterone levels in Rhesus D positive infertile males were insignificantly (p>0.05) higher than Rhesus D negative patients. The study indicated that the incidence of male infertility among individuals with blood group O is consistently higher as compared with other blood groups, suggesting a strong connection between blood group O and male infertility. However, no correlation was found between ABO and Rhesus blood groups and male infertility hormone. But the elevated testosterone levels observed in men with blood group O could represent a possible connection between blood groups and male infertility. |
| format | Article |
| id | doaj-art-aab17fbb6cf44aa9907b0d15d4f212b6 |
| institution | OA Journals |
| issn | 2536-7153 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Hammer Head Production Limited |
| record_format | Article |
| series | Sokoto Journal of Medical Laboratory Science |
| spelling | doaj-art-aab17fbb6cf44aa9907b0d15d4f212b62025-08-20T02:17:04ZengHammer Head Production LimitedSokoto Journal of Medical Laboratory Science2536-71532025-05-01101657A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria.Onitsha, Enebrayi Nelson1*, Okutu Jackson Borobuebi1; Ebizuoye Stow Francis1; Lokoja Ebiweni James1; Ezeiruaku Ferdinand Chukwuma 1; Iniwarikenimi Ebipadei Jeremiah 1; and Oviri Blessing 2Infertility remains a very common global issue that is often associated with several factors such as hormonal, cervical, uterine, immunological or psychological influences. Aside from these factors, there are instances where infertility remains inexplicable. Therefore, further research is required to identify the underlying causes of unexplained infertility. This study assessed the nexus between blood groups and male infertility by evaluating the serum testosterone levels. The study utilized a cross-sectional study design. A total of 200 male within the ages of 18 to 40 years attending fertility clinic at the Federal Medical Centre Yenagoa, Family Care Hospital, Yenagoa, and Tobis Clinic and Consultant between the period of February 2023 and August 2024 were recruited for the study. The subjects consist of 120 known infertile male patients, and 60 apparently healthy fertile males, which served as the control group. Five milliliters of blood was collected following standard procedures and used for the determination of blood groups and testosterone levels using Slide Haem-agglutination technique and Enzyme linked immunosorbent assay (ELISA) technique respectively. Special Package for Social Science version 23.0 was used to perform the statistical analysis, and p-value less than 0.05 was considered statistically significant. The result revealed that the distribution of blood groups in the studied population was 61.7%, 21.7%, 11.7%, and 5.0% for blood groups O, B, A and AB respectively. The Rhesus blood group distribution in the infertile males was 95.0% and 5.0% for Rhesus D positive and negative respectively. The mean values of testosterone in blood group O males were slightly higher than group A, AB and B, but not statistically significant (p>0 . 05) . Furthermore, the mean values of testosterone levels in Rhesus D positive infertile males were insignificantly (p>0.05) higher than Rhesus D negative patients. The study indicated that the incidence of male infertility among individuals with blood group O is consistently higher as compared with other blood groups, suggesting a strong connection between blood group O and male infertility. However, no correlation was found between ABO and Rhesus blood groups and male infertility hormone. But the elevated testosterone levels observed in men with blood group O could represent a possible connection between blood groups and male infertility.https://sokjmls.com.ng/index.php/SJMLS/article/view/657blood groups; infertility; male reproduction; and testosterone |
| spellingShingle | Onitsha, Enebrayi Nelson1*, Okutu Jackson Borobuebi1; Ebizuoye Stow Francis1; Lokoja Ebiweni James1; Ezeiruaku Ferdinand Chukwuma 1; Iniwarikenimi Ebipadei Jeremiah 1; and Oviri Blessing 2 A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. Sokoto Journal of Medical Laboratory Science blood groups; infertility; male reproduction; and testosterone |
| title | A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. |
| title_full | A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. |
| title_fullStr | A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. |
| title_full_unstemmed | A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. |
| title_short | A Comparative Analysis of Blood Groups and Testosterone Levels in Infertile Men in Yenagoa, South-South Nigeria. |
| title_sort | comparative analysis of blood groups and testosterone levels in infertile men in yenagoa south south nigeria |
| topic | blood groups; infertility; male reproduction; and testosterone |
| url | https://sokjmls.com.ng/index.php/SJMLS/article/view/657 |
| work_keys_str_mv | AT onitshaenebrayinelson1okutujacksonborobuebi1ebizuoyestowfrancis1lokojaebiwenijames1ezeiruakuferdinandchukwuma1iniwarikenimiebipadeijeremiah1andoviriblessing2 acomparativeanalysisofbloodgroupsandtestosteronelevelsininfertilemeninyenagoasouthsouthnigeria AT onitshaenebrayinelson1okutujacksonborobuebi1ebizuoyestowfrancis1lokojaebiwenijames1ezeiruakuferdinandchukwuma1iniwarikenimiebipadeijeremiah1andoviriblessing2 comparativeanalysisofbloodgroupsandtestosteronelevelsininfertilemeninyenagoasouthsouthnigeria |