Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex.
<h4>Background</h4>Myelination of white matter in the brain continues throughout adolescence and early adulthood. This cortical immaturity has been suggested as a potential cause of dangerous and impulsive behaviors in adolescence.<h4>Methodology/principal findings</h4>We tes...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2009-08-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006773&type=printable |
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| author | Gregory S Berns Sara Moore C Monica Capra |
| author_facet | Gregory S Berns Sara Moore C Monica Capra |
| author_sort | Gregory S Berns |
| collection | DOAJ |
| description | <h4>Background</h4>Myelination of white matter in the brain continues throughout adolescence and early adulthood. This cortical immaturity has been suggested as a potential cause of dangerous and impulsive behaviors in adolescence.<h4>Methodology/principal findings</h4>We tested this hypothesis in a group of healthy adolescents, age 12-18 (N = 91), who underwent diffusion tensor imaging (DTI) to delineate cortical white matter tracts. As a measure of real-world risk taking, participants completed the Adolescent Risk Questionnaire (ARQ) which measures engagement in dangerous activities. After adjusting for age-related changes in both DTI and ARQ, engagement in dangerous behaviors was found to be positively correlated with fractional anisotropy and negatively correlated with transverse diffusivity in frontal white matter tracts, indicative of increased myelination and/or density of fibers (ages 14-18, N = 60).<h4>Conclusions/significance</h4>The direction of correlation suggests that rather than having immature cortices, adolescents who engage in dangerous activities have frontal white matter tracts that are more adult in form than their more conservative peers. |
| format | Article |
| id | doaj-art-aab0ebcb16c54f03bc19b8edfea78031 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2009-08-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-aab0ebcb16c54f03bc19b8edfea780312025-08-20T02:38:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032009-08-0148e677310.1371/journal.pone.0006773Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex.Gregory S BernsSara MooreC Monica Capra<h4>Background</h4>Myelination of white matter in the brain continues throughout adolescence and early adulthood. This cortical immaturity has been suggested as a potential cause of dangerous and impulsive behaviors in adolescence.<h4>Methodology/principal findings</h4>We tested this hypothesis in a group of healthy adolescents, age 12-18 (N = 91), who underwent diffusion tensor imaging (DTI) to delineate cortical white matter tracts. As a measure of real-world risk taking, participants completed the Adolescent Risk Questionnaire (ARQ) which measures engagement in dangerous activities. After adjusting for age-related changes in both DTI and ARQ, engagement in dangerous behaviors was found to be positively correlated with fractional anisotropy and negatively correlated with transverse diffusivity in frontal white matter tracts, indicative of increased myelination and/or density of fibers (ages 14-18, N = 60).<h4>Conclusions/significance</h4>The direction of correlation suggests that rather than having immature cortices, adolescents who engage in dangerous activities have frontal white matter tracts that are more adult in form than their more conservative peers.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006773&type=printable |
| spellingShingle | Gregory S Berns Sara Moore C Monica Capra Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. PLoS ONE |
| title | Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. |
| title_full | Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. |
| title_fullStr | Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. |
| title_full_unstemmed | Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. |
| title_short | Adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex. |
| title_sort | adolescent engagement in dangerous behaviors is associated with increased white matter maturity of frontal cortex |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006773&type=printable |
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