Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer

Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer

Abstract Background Liver cancer has a high global incidence, particularly in East Asia. Early detection difficulties lead to poor prognosis. Single-cell sequencing precisely identifies gene expression differences in specific cell types, making it valuable in tumor microenvironment research and immu...

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Bibliographic Details
Main Authors: Qunfang Zhou, Jingqiang Wu, Jiaxin Bei, Zixuan Zhai, Xiuzhen Chen, Wei Liang, Jing Meng, Mingyu Liu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Human Genomics
Subjects:
scRNA-seq
Liver cancer
Molecular model
Tumor cell characteristics
Drug exploration
Online Access:https://doi.org/10.1186/s40246-024-00698-2
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