Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review

Background/Objectives: Port-wine stains (PWSs), also known as naevus flammeus or capillary malformations, are congenital cutaneous lesions, typically located in the head/neck area. The manifestations of PWSs include aesthetic and functional impairments due to soft and hard tissue modifications. Stur...

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Main Authors: Andreea Kui, Marius Negucioiu, Smaranda Buduru, Ana-Maria Condor, Daria Chira, Daniela Cornelia Condor, Ondine Patricia Lucaciu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Oral
Subjects:
Online Access:https://www.mdpi.com/2673-6373/5/1/16
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author Andreea Kui
Marius Negucioiu
Smaranda Buduru
Ana-Maria Condor
Daria Chira
Daniela Cornelia Condor
Ondine Patricia Lucaciu
author_facet Andreea Kui
Marius Negucioiu
Smaranda Buduru
Ana-Maria Condor
Daria Chira
Daniela Cornelia Condor
Ondine Patricia Lucaciu
author_sort Andreea Kui
collection DOAJ
description Background/Objectives: Port-wine stains (PWSs), also known as naevus flammeus or capillary malformations, are congenital cutaneous lesions, typically located in the head/neck area. The manifestations of PWSs include aesthetic and functional impairments due to soft and hard tissue modifications. Sturge–Weber syndrome is characterised by additional neuro-ocular manifestations. This systematic review aimed to identify and overview the orodental manifestations of PWSs. Methods: Several databases (PubMed, Web of Science, Scopus, Embase, Cochrane Library) were searched using keywords for PWSs and oral and dental manifestations. The results were centralised, deduplicated, and selected in a two-step sequence. Data were extracted using pre-defined extraction forms and represented graphically and tabulated. The Newcastle–Ottawa and Joanna Briggs Institute scales were used for quality assessment. Results: Out of 884 results, 43 studies were selected for inclusion. Eleven studies investigated patients diagnosed with PWSs, while thirty-two studies investigated SWS patients. Regarding study designs, eight studies were retrospective, one was cross-sectional, two were case series, and thirty-two were case reports. The most frequently mentioned manifestations were gingival hypertrophy, lip hypertrophy, mucosal or gingival staining, malocclusion, gingivitis or gingival bleeding, and facial asymmetry. Conclusions: Due to the rarity of this pathology, the orodental manifestations of PWSs are not widely known to dentists. Soft tissue hypertrophy, malocclusion, and bony hypertrophy are significant concerns that need to be addressed during treatment.
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spelling doaj-art-aaaae87d747b4f1fb74116f5cdb803d82025-08-20T02:42:24ZengMDPI AGOral2673-63732025-03-01511610.3390/oral5010016Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic ReviewAndreea Kui0Marius Negucioiu1Smaranda Buduru2Ana-Maria Condor3Daria Chira4Daniela Cornelia Condor5Ondine Patricia Lucaciu6Prosthetic Dentistry Discipline, Department 4—Prosthetic Dentistry and Dental Materials, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400008 Cluj-Napoca, RomaniaProsthetic Dentistry Discipline, Department 4—Prosthetic Dentistry and Dental Materials, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400008 Cluj-Napoca, RomaniaProsthetic Dentistry Discipline, Department 4—Prosthetic Dentistry and Dental Materials, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400008 Cluj-Napoca, RomaniaProsthetic Dentistry Discipline, Department 4—Prosthetic Dentistry and Dental Materials, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400008 Cluj-Napoca, RomaniaProsthetic Dentistry Discipline, Department 4—Prosthetic Dentistry and Dental Materials, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400008 Cluj-Napoca, RomaniaPeriodontics Discipline, Department 3—Oral Rehabilitation, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, RomaniaOral Health Discipline, Department 3—Oral Rehabilitation, Faculty of Dental Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, RomaniaBackground/Objectives: Port-wine stains (PWSs), also known as naevus flammeus or capillary malformations, are congenital cutaneous lesions, typically located in the head/neck area. The manifestations of PWSs include aesthetic and functional impairments due to soft and hard tissue modifications. Sturge–Weber syndrome is characterised by additional neuro-ocular manifestations. This systematic review aimed to identify and overview the orodental manifestations of PWSs. Methods: Several databases (PubMed, Web of Science, Scopus, Embase, Cochrane Library) were searched using keywords for PWSs and oral and dental manifestations. The results were centralised, deduplicated, and selected in a two-step sequence. Data were extracted using pre-defined extraction forms and represented graphically and tabulated. The Newcastle–Ottawa and Joanna Briggs Institute scales were used for quality assessment. Results: Out of 884 results, 43 studies were selected for inclusion. Eleven studies investigated patients diagnosed with PWSs, while thirty-two studies investigated SWS patients. Regarding study designs, eight studies were retrospective, one was cross-sectional, two were case series, and thirty-two were case reports. The most frequently mentioned manifestations were gingival hypertrophy, lip hypertrophy, mucosal or gingival staining, malocclusion, gingivitis or gingival bleeding, and facial asymmetry. Conclusions: Due to the rarity of this pathology, the orodental manifestations of PWSs are not widely known to dentists. Soft tissue hypertrophy, malocclusion, and bony hypertrophy are significant concerns that need to be addressed during treatment.https://www.mdpi.com/2673-6373/5/1/16port-wine stainsSturge–Weber syndromeoral healthoral manifestationslip hypertrophy
spellingShingle Andreea Kui
Marius Negucioiu
Smaranda Buduru
Ana-Maria Condor
Daria Chira
Daniela Cornelia Condor
Ondine Patricia Lucaciu
Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
Oral
port-wine stains
Sturge–Weber syndrome
oral health
oral manifestations
lip hypertrophy
title Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
title_full Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
title_fullStr Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
title_full_unstemmed Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
title_short Port-Wine Stains’ Orodental Manifestations and Complications: A Systematic Review
title_sort port wine stains orodental manifestations and complications a systematic review
topic port-wine stains
Sturge–Weber syndrome
oral health
oral manifestations
lip hypertrophy
url https://www.mdpi.com/2673-6373/5/1/16
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