Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer

BackgroundWhile surgery remains the standard treatment for tongue cancer, it is associated with a range of functional and aesthetic sequelae. Additionally, ultrasound-guided microwave ablation (MWA) represents a promising minimally invasive alternative for patients with poor performance status or th...

Full description

Saved in:
Bibliographic Details
Main Authors: Ting Wei, Jiulong Dai, Tingting Li, Ziyue Hu, Lu Wang, Juan Li, Jie Zou, Jia Feng, Man Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1564348/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849429720638160896
author Ting Wei
Jiulong Dai
Tingting Li
Ziyue Hu
Lu Wang
Juan Li
Jie Zou
Jia Feng
Man Lu
author_facet Ting Wei
Jiulong Dai
Tingting Li
Ziyue Hu
Lu Wang
Juan Li
Jie Zou
Jia Feng
Man Lu
author_sort Ting Wei
collection DOAJ
description BackgroundWhile surgery remains the standard treatment for tongue cancer, it is associated with a range of functional and aesthetic sequelae. Additionally, ultrasound-guided microwave ablation (MWA) represents a promising minimally invasive alternative for patients with poor performance status or those unwilling to undergo surgery.Case PresentationWe report a 50-year-old male patient diagnosed with advanced tongue squamous cell carcinoma and cervical lymph node metastases. Microwave ablation was performed using a power setting of 30 W. Contrast-enhanced ultrasound conducted immediately afterward revealed no enhancement in the ablation area. Following the ablation, the patient received adjuvant radiotherapy and chemotherapy. During the procedure, the patient experienced minimal pain and no significant complications. After more than two years of follow-up, no evidence of metastasis or recurrence was observed, and the patient retained normal speech and swallowing functions.ConclusionsUltrasound-guided MWA combined with radiotherapy and chemotherapy offers a safe, effective, and minimally invasive approach to the treatment of advanced tongue cancer.
format Article
id doaj-art-aaa8d700ee4b4c25831847787f1ba822
institution Kabale University
issn 2234-943X
language English
publishDate 2025-07-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-aaa8d700ee4b4c25831847787f1ba8222025-08-20T03:28:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-07-011510.3389/fonc.2025.15643481564348Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancerTing WeiJiulong DaiTingting LiZiyue HuLu WangJuan LiJie ZouJia FengMan LuBackgroundWhile surgery remains the standard treatment for tongue cancer, it is associated with a range of functional and aesthetic sequelae. Additionally, ultrasound-guided microwave ablation (MWA) represents a promising minimally invasive alternative for patients with poor performance status or those unwilling to undergo surgery.Case PresentationWe report a 50-year-old male patient diagnosed with advanced tongue squamous cell carcinoma and cervical lymph node metastases. Microwave ablation was performed using a power setting of 30 W. Contrast-enhanced ultrasound conducted immediately afterward revealed no enhancement in the ablation area. Following the ablation, the patient received adjuvant radiotherapy and chemotherapy. During the procedure, the patient experienced minimal pain and no significant complications. After more than two years of follow-up, no evidence of metastasis or recurrence was observed, and the patient retained normal speech and swallowing functions.ConclusionsUltrasound-guided MWA combined with radiotherapy and chemotherapy offers a safe, effective, and minimally invasive approach to the treatment of advanced tongue cancer.https://www.frontiersin.org/articles/10.3389/fonc.2025.1564348/fullultrasonographymicrowave ablationtongue neoplasmsradiotherapydrug therapy
spellingShingle Ting Wei
Jiulong Dai
Tingting Li
Ziyue Hu
Lu Wang
Juan Li
Jie Zou
Jia Feng
Man Lu
Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
Frontiers in Oncology
ultrasonography
microwave ablation
tongue neoplasms
radiotherapy
drug therapy
title Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
title_full Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
title_fullStr Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
title_full_unstemmed Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
title_short Case Report: Ultrasound-guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
title_sort case report ultrasound guided microwave ablation combined with postoperative radiotherapy and chemotherapy for advanced tongue cancer
topic ultrasonography
microwave ablation
tongue neoplasms
radiotherapy
drug therapy
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1564348/full
work_keys_str_mv AT tingwei casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT jiulongdai casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT tingtingli casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT ziyuehu casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT luwang casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT juanli casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT jiezou casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT jiafeng casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer
AT manlu casereportultrasoundguidedmicrowaveablationcombinedwithpostoperativeradiotherapyandchemotherapyforadvancedtonguecancer