Advancements in <i>p53</i>-Based Anti-Tumor Gene Therapy Research
The <i>p53</i> gene is one of the genes most closely associated with human tumors and has become a popular target for tumor drug design. Currently, <i>p53</i>-based gene therapy techniques have been developed, but these therapies face challenges such as immaturity, high safet...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/29/22/5315 |
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| Summary: | The <i>p53</i> gene is one of the genes most closely associated with human tumors and has become a popular target for tumor drug design. Currently, <i>p53</i>-based gene therapy techniques have been developed, but these therapies face challenges such as immaturity, high safety hazards, limited efficacy, and low patient acceptance. However, researchers are no less enthusiastic about the treatment because of its theoretical potential to treat cancer. In this paper, the advances in <i>p53</i>-based gene therapy and related nucleic acid delivery technologies were reviewed and prospected in order to support further development in this field. |
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| ISSN: | 1420-3049 |