Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking

Abstract Tomato (Solanum lycopersicum L.), one of the most widely grown vegetable crops in the world, faces cracking problems before and after harvest. Fruit cracking reduces the commercial value and seriously affects the economic performance of the fruits by affecting the appearance and quality of...

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Main Authors: Zhaojiang Zhong, Zhen Wu, Rong Zhou, Xiaowei Yu, Yuanyuan Zhou, Yinghao Zhai, Haowei Lin, Fangling Jiang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Plant Biology
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Online Access:https://doi.org/10.1186/s12870-024-05937-1
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author Zhaojiang Zhong
Zhen Wu
Rong Zhou
Xiaowei Yu
Yuanyuan Zhou
Yinghao Zhai
Haowei Lin
Fangling Jiang
author_facet Zhaojiang Zhong
Zhen Wu
Rong Zhou
Xiaowei Yu
Yuanyuan Zhou
Yinghao Zhai
Haowei Lin
Fangling Jiang
author_sort Zhaojiang Zhong
collection DOAJ
description Abstract Tomato (Solanum lycopersicum L.), one of the most widely grown vegetable crops in the world, faces cracking problems before and after harvest. Fruit cracking reduces the commercial value and seriously affects the economic performance of the fruits by affecting the appearance and quality of the fruit. Clarifying the molecular mechanism underlying tomato fruit cracking is of great importance for selecting and breeding cracking-resistant varieties. At present, research on the molecular mechanism of tomato fruit cracking has made progress, but few studies have been conducted to explore the genes related to fruit cracking regulation using combined multi-omics analysis. We applied Ribo-seq (ribosome analysis sequencing) and RNA-seq (RNA-sequencing) techniques to uncover potential fruit cracking regulatory genes and improve the regulatory network of fruit cracking using extremely cracking-resistant (CR) and cracking-susceptible (CS) tomato genotypes. Combining these two sets of histological data and translation efficiency, 41 genes were identified to be associated with fruit cracking. The genes played functions on hormone synthesis (e.g. Solyc09g089580.4, Solyc07g049530.3), reactive oxygen species regulation (e.g. Solyc08g080940.3), cell wall metabolism (e.g. Solyc04g071070.2, Solyc03g123630.4), aquaporins activity (e.g. Solyc03g096290.3, Solyc10g083880.2), cuticle and wax composition, as well as mineral elements transport (e.g. Solyc10g006660.3, Solyc01g057770.3), while 10 of them were transcription factors (TF) (e.g. Solyc05g015850.4, Solyc08g078190.2). Based on the investigation of the interaction relationship between these genes, the synergistic regulation of multi-gene tomato fruit cracking was predicted. This study suggests that the synergistic action of transcription and translation is an important molecular mechanism in regulating tomato fruit cracking.
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issn 1471-2229
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publishDate 2024-12-01
publisher BMC
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spelling doaj-art-aa978a06537f484c85d333d5d232afdb2025-08-20T01:57:15ZengBMCBMC Plant Biology1471-22292024-12-0124111810.1186/s12870-024-05937-1Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit crackingZhaojiang Zhong0Zhen Wu1Rong Zhou2Xiaowei Yu3Yuanyuan Zhou4Yinghao Zhai5Haowei Lin6Fangling Jiang7Nanjing Agricultural UniversityNanjing Agricultural UniversityNanjing Agricultural UniversityNanjing Agricultural UniversityKunshan Youlaigu Science and Technology Innovation CenterNanjing Agricultural UniversityNanjing Agricultural UniversityNanjing Agricultural UniversityAbstract Tomato (Solanum lycopersicum L.), one of the most widely grown vegetable crops in the world, faces cracking problems before and after harvest. Fruit cracking reduces the commercial value and seriously affects the economic performance of the fruits by affecting the appearance and quality of the fruit. Clarifying the molecular mechanism underlying tomato fruit cracking is of great importance for selecting and breeding cracking-resistant varieties. At present, research on the molecular mechanism of tomato fruit cracking has made progress, but few studies have been conducted to explore the genes related to fruit cracking regulation using combined multi-omics analysis. We applied Ribo-seq (ribosome analysis sequencing) and RNA-seq (RNA-sequencing) techniques to uncover potential fruit cracking regulatory genes and improve the regulatory network of fruit cracking using extremely cracking-resistant (CR) and cracking-susceptible (CS) tomato genotypes. Combining these two sets of histological data and translation efficiency, 41 genes were identified to be associated with fruit cracking. The genes played functions on hormone synthesis (e.g. Solyc09g089580.4, Solyc07g049530.3), reactive oxygen species regulation (e.g. Solyc08g080940.3), cell wall metabolism (e.g. Solyc04g071070.2, Solyc03g123630.4), aquaporins activity (e.g. Solyc03g096290.3, Solyc10g083880.2), cuticle and wax composition, as well as mineral elements transport (e.g. Solyc10g006660.3, Solyc01g057770.3), while 10 of them were transcription factors (TF) (e.g. Solyc05g015850.4, Solyc08g078190.2). Based on the investigation of the interaction relationship between these genes, the synergistic regulation of multi-gene tomato fruit cracking was predicted. This study suggests that the synergistic action of transcription and translation is an important molecular mechanism in regulating tomato fruit cracking.https://doi.org/10.1186/s12870-024-05937-1TomatoCrackingRNA-sequencingRibosome profiling sequencingTranslation efficiency
spellingShingle Zhaojiang Zhong
Zhen Wu
Rong Zhou
Xiaowei Yu
Yuanyuan Zhou
Yinghao Zhai
Haowei Lin
Fangling Jiang
Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
BMC Plant Biology
Tomato
Cracking
RNA-sequencing
Ribosome profiling sequencing
Translation efficiency
title Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
title_full Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
title_fullStr Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
title_full_unstemmed Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
title_short Ribo-seq and RNA-seq analyses enrich the regulatory network of tomato fruit cracking
title_sort ribo seq and rna seq analyses enrich the regulatory network of tomato fruit cracking
topic Tomato
Cracking
RNA-sequencing
Ribosome profiling sequencing
Translation efficiency
url https://doi.org/10.1186/s12870-024-05937-1
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