Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism
11Beta-hydroxysteroid dehydrogenase 1 (11β-HSD1) is a key enzyme involved in metabolic syndrome. Transcript-specific epigenetic regulation of the gene encoding 11β-HSD1 (HSD11B1) has been reported. We examined the mRNA level and methylation status of the HSD11B1 promoter region in the adipose tissue...
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Main Authors: | Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Shin-ichi Horike, Makiko Meguro-Horike, Takashi Yoneda, Yoshiyu Takeda |
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Format: | Article |
Language: | English |
Published: |
The Japan Endocrine Society
2024-03-01
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Series: | Endocrine Journal |
Subjects: | |
Online Access: | https://www.jstage.jst.go.jp/article/endocrj/71/3/71_EJ23-0103/_html/-char/en |
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