Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy
Hepatitis C virus infection is the leading cause of chronic liver disease in the United States of America. Pegylated interferon α and ribavirin combination is the mainstay of treatment. Severe pulmonary toxicities are rarely reported. We report here a case of severe form of organizing pneumonia seco...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2015/794592 |
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| _version_ | 1832560334937784320 |
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| author | Amit Chopra Creticus Marak Narendrakumar Alappan Chang Shim |
| author_facet | Amit Chopra Creticus Marak Narendrakumar Alappan Chang Shim |
| author_sort | Amit Chopra |
| collection | DOAJ |
| description | Hepatitis C virus infection is the leading cause of chronic liver disease in the United States of America. Pegylated interferon α and ribavirin combination is the mainstay of treatment. Severe pulmonary toxicities are rarely reported. We report here a case of severe form of organizing pneumonia secondary to pegylated interferon α therapy presenting as acute respiratory failure. Patient has near complete recovery with withdrawal of pegylated interferon α and steroid therapy. We report this case to raise the awareness of this rare but potentially life-threatening pulmonary complication of pegylated interferon α therapy. |
| format | Article |
| id | doaj-art-aa8e84730e56410b9261eaef1c0270d9 |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-aa8e84730e56410b9261eaef1c0270d92025-02-03T01:27:51ZengWileyCase Reports in Pulmonology2090-68462090-68542015-01-01201510.1155/2015/794592794592Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin TherapyAmit Chopra0Creticus Marak1Narendrakumar Alappan2Chang Shim3Division of Pulmonary and Critical Care, Albany Medical Center, Albany, NY, USADivision of Pulmonary and Critical Care, National Jewish Health, Denver, CO, USADivision of Pulmonary and Critical Care, Cleveland Clinic, Cleveland, OH, USADivision of Pulmonary and Critical Care, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USAHepatitis C virus infection is the leading cause of chronic liver disease in the United States of America. Pegylated interferon α and ribavirin combination is the mainstay of treatment. Severe pulmonary toxicities are rarely reported. We report here a case of severe form of organizing pneumonia secondary to pegylated interferon α therapy presenting as acute respiratory failure. Patient has near complete recovery with withdrawal of pegylated interferon α and steroid therapy. We report this case to raise the awareness of this rare but potentially life-threatening pulmonary complication of pegylated interferon α therapy.http://dx.doi.org/10.1155/2015/794592 |
| spellingShingle | Amit Chopra Creticus Marak Narendrakumar Alappan Chang Shim Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy Case Reports in Pulmonology |
| title | Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy |
| title_full | Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy |
| title_fullStr | Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy |
| title_full_unstemmed | Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy |
| title_short | Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy |
| title_sort | organizing pneumonia associated with pegylated interferon α and ribavirin therapy |
| url | http://dx.doi.org/10.1155/2015/794592 |
| work_keys_str_mv | AT amitchopra organizingpneumoniaassociatedwithpegylatedinterferonaandribavirintherapy AT creticusmarak organizingpneumoniaassociatedwithpegylatedinterferonaandribavirintherapy AT narendrakumaralappan organizingpneumoniaassociatedwithpegylatedinterferonaandribavirintherapy AT changshim organizingpneumoniaassociatedwithpegylatedinterferonaandribavirintherapy |