Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy
We evaluated the efficacy of percutaneous ethanol injection therapy (PEIT) as a therapeutic option for recurrence of secondary hyperparathyroidism after subtotal parathyroidectomy in ESRD patients. Six patients underwent PEIT. A mean of 1.3 ± 0.8 ethanol injections was performed. Nodular volume was...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.4061/2011/246734 |
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| author | Walter G. Douthat Gabriela Cardozo Gabriela Garay Santiago Orozco Carlos Chiurchiu Jorge de la Fuente Javier de Arteaga Pablo U. Massari |
| author_facet | Walter G. Douthat Gabriela Cardozo Gabriela Garay Santiago Orozco Carlos Chiurchiu Jorge de la Fuente Javier de Arteaga Pablo U. Massari |
| author_sort | Walter G. Douthat |
| collection | DOAJ |
| description | We evaluated the efficacy of percutaneous ethanol injection therapy (PEIT) as a therapeutic option for recurrence of secondary hyperparathyroidism after subtotal parathyroidectomy in ESRD patients. Six patients underwent PEIT. A mean of 1.3 ± 0.8 ethanol injections was performed. Nodular volume was 1.5 ± 1.7 cm3, and 2.8 ± 2.8 cm3 of ethanol was injected per patient. After ethanol injection PTH decreased significantly (1897 ± 754 to 549 ± 863 pg/mL (P<.01)). There was also a reduction in serum calcium, phosphorus and calcium-phosphorus product. A positive and significant correlation was found between nodular volume with ethanol injected and time from parathyroidectomy. Only one patient required hospitalization due to severe hypocalcaemia. In other two cases, local discomfort and temporary mild dysphonia were registered. PEIT is an effective treatment to control recurrences of secondary hyperparathyroidism postsubtotal parathyroidectomy. |
| format | Article |
| id | doaj-art-aa8dc6595d3e49c1b0eefbb7deb7888c |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-aa8dc6595d3e49c1b0eefbb7deb7888c2025-02-03T01:30:33ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/246734246734Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal ParathyroidectomyWalter G. Douthat0Gabriela Cardozo1Gabriela Garay2Santiago Orozco3Carlos Chiurchiu4Jorge de la Fuente5Javier de Arteaga6Pablo U. Massari7Bone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaBone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaClinical Chemistry Laboratory, Hospital Privado-Centro Médico de Córdoba, 5016 Córdoba, ArgentinaDepartment of Radiology, Hospital Privado-Centro Médico de Córdoba, 5016 Córdoba, ArgentinaBone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaBone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaBone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaBone and Mineral Metabolism Section, Renal Service, Hospital Privado-Centro Médico de Córdoba, Postgraduate School of Nephrology, Catholic University of Córdoba, Naciones Unidas 346, 5016 Córdoba, ArgentinaWe evaluated the efficacy of percutaneous ethanol injection therapy (PEIT) as a therapeutic option for recurrence of secondary hyperparathyroidism after subtotal parathyroidectomy in ESRD patients. Six patients underwent PEIT. A mean of 1.3 ± 0.8 ethanol injections was performed. Nodular volume was 1.5 ± 1.7 cm3, and 2.8 ± 2.8 cm3 of ethanol was injected per patient. After ethanol injection PTH decreased significantly (1897 ± 754 to 549 ± 863 pg/mL (P<.01)). There was also a reduction in serum calcium, phosphorus and calcium-phosphorus product. A positive and significant correlation was found between nodular volume with ethanol injected and time from parathyroidectomy. Only one patient required hospitalization due to severe hypocalcaemia. In other two cases, local discomfort and temporary mild dysphonia were registered. PEIT is an effective treatment to control recurrences of secondary hyperparathyroidism postsubtotal parathyroidectomy.http://dx.doi.org/10.4061/2011/246734 |
| spellingShingle | Walter G. Douthat Gabriela Cardozo Gabriela Garay Santiago Orozco Carlos Chiurchiu Jorge de la Fuente Javier de Arteaga Pablo U. Massari Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy International Journal of Nephrology |
| title | Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy |
| title_full | Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy |
| title_fullStr | Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy |
| title_full_unstemmed | Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy |
| title_short | Use of Percutaneous Ethanol Injection Therapy for Recurrent Secondary Hyperparathyroidism after Subtotal Parathyroidectomy |
| title_sort | use of percutaneous ethanol injection therapy for recurrent secondary hyperparathyroidism after subtotal parathyroidectomy |
| url | http://dx.doi.org/10.4061/2011/246734 |
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