The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss

The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss

IntroductionAdipose tissue inflammation, driven in part by immune cells, may contribute to the elevated type 2 diabetes risk in adults with childhood-onset obesity (CO) compared to those with adult-onset obesity (AO). Weight loss can modify adipose tissue immune cell composition, but whether these c...

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Bibliographic Details
Main Authors: Jessica Murphy, José A. Morais, Michael A. Tsoukas, Alexandra B. Cooke, Stella S. Daskalopoulou, Sylvia Santosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
obesity
age of onset
subcutaneous adipose tissue
macrophages
T cells
adipokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601847/full
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