Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle
The antioxidant potential of Crataegus azarolus Var. aronia aqueous extract was used as reducing and stabilizing media to the green synthesis of bioactive CuO@Fe3O4@Walnut shell nanocomposite (NCs). The ability of the plant extract as bioreducing medium was proved using Fourier-transform infrared sp...
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Erbil Polytechnic University
2021-06-01
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| Series: | Polytechnic Journal |
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| Online Access: | https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/21 |
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| author | Sarbast A. Mahmud |
| author_facet | Sarbast A. Mahmud |
| author_sort | Sarbast A. Mahmud |
| collection | DOAJ |
| description | The antioxidant potential of Crataegus azarolus Var. aronia aqueous extract was used as reducing and
stabilizing media to the green synthesis of bioactive CuO@Fe3O4@Walnut shell nanocomposite (NCs).
The ability of the plant extract as bioreducing medium was proved using Fourier-transform infrared
spectroscopy and ultraviolet–visible spectroscopy. While, the structural identification of synthesized
CuO@Fe3O4@Walnut shell NCs was proved using the scanning electron microscopy, electron dispersive
spectroscopy, elemental mapping, and point analysis. Then, the antivasoconstriction effects of CuO@
Fe3O4@Walnut shell NCs (5*10−2 mg/
ml) and (1*10−1 mg/
ml) on rats isolated thoracic aortic smooth
muscle cells were studied. Green synthesized CuO@Fe3O4@Walnut shell NCs showed effective
antivasoconstriction activity against norepinephrine (NE) (1*10−9–10−4 M) induced contraction in
endothelium-intact and endothelium-denuded rats aortic smooth muscle. In conclusion, the aqueous
extract of C. aronia acts as potential reducing and stabilizing media to the green synthesis of bioactive
CuO@Fe3O4@Walnut shell NCs and the NCs play an important role against contractile effects of NE
on rats’ aortic smooth muscle. |
| format | Article |
| id | doaj-art-aa64c83a84d04ddbaaf3b7b288b3f1cd |
| institution | OA Journals |
| issn | 2707-7799 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Erbil Polytechnic University |
| record_format | Article |
| series | Polytechnic Journal |
| spelling | doaj-art-aa64c83a84d04ddbaaf3b7b288b3f1cd2025-08-20T01:59:52ZengErbil Polytechnic UniversityPolytechnic Journal2707-77992021-06-01111118125https://doi.org/10.25156/ptj.v11n1y2021.pp118-125Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth MuscleSarbast A. Mahmud0Department of Biology, Faculty of Science, Soran University, Soran, Kurdistan Regional, IraqThe antioxidant potential of Crataegus azarolus Var. aronia aqueous extract was used as reducing and stabilizing media to the green synthesis of bioactive CuO@Fe3O4@Walnut shell nanocomposite (NCs). The ability of the plant extract as bioreducing medium was proved using Fourier-transform infrared spectroscopy and ultraviolet–visible spectroscopy. While, the structural identification of synthesized CuO@Fe3O4@Walnut shell NCs was proved using the scanning electron microscopy, electron dispersive spectroscopy, elemental mapping, and point analysis. Then, the antivasoconstriction effects of CuO@ Fe3O4@Walnut shell NCs (5*10−2 mg/ ml) and (1*10−1 mg/ ml) on rats isolated thoracic aortic smooth muscle cells were studied. Green synthesized CuO@Fe3O4@Walnut shell NCs showed effective antivasoconstriction activity against norepinephrine (NE) (1*10−9–10−4 M) induced contraction in endothelium-intact and endothelium-denuded rats aortic smooth muscle. In conclusion, the aqueous extract of C. aronia acts as potential reducing and stabilizing media to the green synthesis of bioactive CuO@Fe3O4@Walnut shell NCs and the NCs play an important role against contractile effects of NE on rats’ aortic smooth muscle.https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/21aortic smooth muscle;crataegus aronia;green synthesis;nanocomposite |
| spellingShingle | Sarbast A. Mahmud Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle Polytechnic Journal aortic smooth muscle; crataegus aronia; green synthesis; nanocomposite |
| title | Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle |
| title_full | Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle |
| title_fullStr | Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle |
| title_full_unstemmed | Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle |
| title_short | Green Synthesis of Bioactive CuO@Fe3 O4 @Walnut Shell Nanocomposite Using Crataegus azarolus Var. aronia L. Extract and its Antivasoconstrictive Action on Rat’s Aortic Smooth Muscle |
| title_sort | green synthesis of bioactive cuo fe3 o4 walnut shell nanocomposite using crataegus azarolus var aronia l extract and its antivasoconstrictive action on rat s aortic smooth muscle |
| topic | aortic smooth muscle; crataegus aronia; green synthesis; nanocomposite |
| url | https://polytechnic-journal.epu.edu.iq/home/vol11/iss1/21 |
| work_keys_str_mv | AT sarbastamahmud greensynthesisofbioactivecuofe3o4walnutshellnanocompositeusingcrataegusazarolusvararonialextractanditsantivasoconstrictiveactiononratsaorticsmoothmuscle |