Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management

Glaucoma is the leading cause of irreversible blindness worldwide and the prevalence is on the rising trend. Intraocular pressure (IOP) reduction is the mainstay of treatment. The current practice of IOP monitoring is based on spot measurements during clinic visits during office hours. However, ther...

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Main Authors: Chun Hing Ho, Jasper K. W. Wong
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/3632197
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author Chun Hing Ho
Jasper K. W. Wong
author_facet Chun Hing Ho
Jasper K. W. Wong
author_sort Chun Hing Ho
collection DOAJ
description Glaucoma is the leading cause of irreversible blindness worldwide and the prevalence is on the rising trend. Intraocular pressure (IOP) reduction is the mainstay of treatment. The current practice of IOP monitoring is based on spot measurements during clinic visits during office hours. However, there are up to 50% of glaucoma patients who had normal initial IOP, while some treated patients continued to have progressive glaucomatous optic nerve damage even with a low IOP. Recent studies have shown that the IOP of glaucoma patients fluctuated during the day with different patterns, and some of them had peak IOP outside office hours. These findings provided us with new insights on the role of 24-hour IOP monitoring in managing normal tension glaucoma and patients with progressive deterioration despite apparently well-controlled IOP. Nevertheless, results to date are rather inconsistent, and there is no consensus yet. In this review, we briefly highlighted the current modalities of 24-hour IOP monitoring and summarized the characteristic 24-hour IOP pattern and the clinical relevance of IOP parameters in predicting glaucomatous progression in different glaucoma subtypes. We also discussed the therapeutic efficacy of current glaucoma treatment modalities with respect to the mentioned 24-hour IOP profiles, so as to strengthen the role of 24-hour IOP monitoring in identifying and stratifying the risks of progression in glaucoma patients, as well as optimizing treatments according to their IOP profiles.
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spelling doaj-art-aa55938761de4106b703ca8ef0cd691d2025-08-20T02:20:38ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/36321973632197Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma ManagementChun Hing Ho0Jasper K. W. Wong1Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong KongDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong KongGlaucoma is the leading cause of irreversible blindness worldwide and the prevalence is on the rising trend. Intraocular pressure (IOP) reduction is the mainstay of treatment. The current practice of IOP monitoring is based on spot measurements during clinic visits during office hours. However, there are up to 50% of glaucoma patients who had normal initial IOP, while some treated patients continued to have progressive glaucomatous optic nerve damage even with a low IOP. Recent studies have shown that the IOP of glaucoma patients fluctuated during the day with different patterns, and some of them had peak IOP outside office hours. These findings provided us with new insights on the role of 24-hour IOP monitoring in managing normal tension glaucoma and patients with progressive deterioration despite apparently well-controlled IOP. Nevertheless, results to date are rather inconsistent, and there is no consensus yet. In this review, we briefly highlighted the current modalities of 24-hour IOP monitoring and summarized the characteristic 24-hour IOP pattern and the clinical relevance of IOP parameters in predicting glaucomatous progression in different glaucoma subtypes. We also discussed the therapeutic efficacy of current glaucoma treatment modalities with respect to the mentioned 24-hour IOP profiles, so as to strengthen the role of 24-hour IOP monitoring in identifying and stratifying the risks of progression in glaucoma patients, as well as optimizing treatments according to their IOP profiles.http://dx.doi.org/10.1155/2019/3632197
spellingShingle Chun Hing Ho
Jasper K. W. Wong
Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
Journal of Ophthalmology
title Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
title_full Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
title_fullStr Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
title_full_unstemmed Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
title_short Role of 24-Hour Intraocular Pressure Monitoring in Glaucoma Management
title_sort role of 24 hour intraocular pressure monitoring in glaucoma management
url http://dx.doi.org/10.1155/2019/3632197
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