A Society-to-Cells approach to evaluating multilevel and interrelated drivers of breast cancer disparities in Black women

Abstract Despite advances in detection and treatment, Black women in the US continue to experience more aggressive breast cancer subtypes and higher mortality. Framed through a Society-to-Cells lens, this review presents a comprehensive framework for understanding how multilevel drivers—from structu...

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Bibliographic Details
Main Authors: Maurade Gormley, Wayne R. Lawrence, Jesse J. Plascak, Electra D. Paskett, Coral Omene, Adana A. M. Llanos
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00812-0
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Summary:Abstract Despite advances in detection and treatment, Black women in the US continue to experience more aggressive breast cancer subtypes and higher mortality. Framed through a Society-to-Cells lens, this review presents a comprehensive framework for understanding how multilevel drivers—from structural forces to cellular responses—interact to perpetuate disparities. Addressing these inequities requires systemic reforms targeting root causes, including policies to redress historical neighborhood disinvestment and eliminate bias within healthcare systems.
ISSN:2374-4677