Domoic Acid-Induced Neurotoxicity Is Mainly Mediated by the AMPA/KA Receptor: Comparison between Immature and Mature Primary Cultures of Neurons and Glial Cells from Rat Cerebellum

Domoic acid (DomA) is a naturally occurring shellfish toxin that can induce brain damage in mammalians. Neonates have shown increased sensitivity to DomA-induced toxicity, and prenatal exposure has been associated with e.g. decreased brain GABA levels, and increased glutamate levels. Here, we evalua...

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Bibliographic Details
Main Authors: Helena T. Hogberg, Anna K. Bal-Price
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2011/543512
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