Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome

Background: Cervico-Oculo-acoustic syndrome, also known as Wildervanck syndrome, is a rare inherited disorder that causes congenital hearing loss, Klippel-Feil abnormalities, and Duane retraction syndrome. Females are more likely to have Wildervanck syndrome and associated skeletal and cranial anoma...

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Main Authors: Dipti Shikha Kashyap E, Mohit Kumar
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2025-06-01
Series:Journal of Ophthalmology
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Online Access:https://ua.ozhurnal.com/index.php/files/article/view/239
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author Dipti Shikha Kashyap E
Mohit Kumar
author_facet Dipti Shikha Kashyap E
Mohit Kumar
author_sort Dipti Shikha Kashyap E
collection DOAJ
description Background: Cervico-Oculo-acoustic syndrome, also known as Wildervanck syndrome, is a rare inherited disorder that causes congenital hearing loss, Klippel-Feil abnormalities, and Duane retraction syndrome. Females are more likely to have Wildervanck syndrome and associated skeletal and cranial anomalies. This illness's distinctive symptoms must be accurately documented to advance clinical knowledge and therapeutic strategies. Case Presentation: An eleven-year-old girl from a blood line had restricted neck movement and left eye abduction since birth. She had genu valgum, arachnodactyly, micrognathia, and other notable cranial anomalies. Interventions: Supportive treatment included neck mobility and scoliosis therapy, hearing aids for her conductive hearing loss, and genu valgum assessments. Genetic consultation assisted with family planning and inheritance patterns. Conclusion: As this example shows a rare phenotype, patients with Wildervanck syndrome may have more symptoms than previously considered. This patient’s limb malformations underscore the need for thorough clinical examination and genetic research. This paper provides a good starting point for comprehensive Wildervanck syndrome diagnosis, treatment, and genetic counseling.
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spelling doaj-art-aa4eb714a9a14e26b44bb94402bc945e2025-08-20T03:31:33ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402025-06-0134549https://doi.org/10.31288/oftalmolzh202534549Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndromeDipti Shikha Kashyap E0Mohit Kumar1SIC Medical College and Hospital FaridabadSIC Medical College and Hospital FaridabadBackground: Cervico-Oculo-acoustic syndrome, also known as Wildervanck syndrome, is a rare inherited disorder that causes congenital hearing loss, Klippel-Feil abnormalities, and Duane retraction syndrome. Females are more likely to have Wildervanck syndrome and associated skeletal and cranial anomalies. This illness's distinctive symptoms must be accurately documented to advance clinical knowledge and therapeutic strategies. Case Presentation: An eleven-year-old girl from a blood line had restricted neck movement and left eye abduction since birth. She had genu valgum, arachnodactyly, micrognathia, and other notable cranial anomalies. Interventions: Supportive treatment included neck mobility and scoliosis therapy, hearing aids for her conductive hearing loss, and genu valgum assessments. Genetic consultation assisted with family planning and inheritance patterns. Conclusion: As this example shows a rare phenotype, patients with Wildervanck syndrome may have more symptoms than previously considered. This patient’s limb malformations underscore the need for thorough clinical examination and genetic research. This paper provides a good starting point for comprehensive Wildervanck syndrome diagnosis, treatment, and genetic counseling.https://ua.ozhurnal.com/index.php/files/article/view/239genu valgumarachnodactylywildervanck syndromeklippel-feil abnormalitiesduane retraction syndrome
spellingShingle Dipti Shikha Kashyap E
Mohit Kumar
Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
Journal of Ophthalmology
genu valgum
arachnodactyly
wildervanck syndrome
klippel-feil abnormalities
duane retraction syndrome
title Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
title_full Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
title_fullStr Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
title_full_unstemmed Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
title_short Genu valgum and arachnodactyly: a rare presentation in Wildervanck syndrome
title_sort genu valgum and arachnodactyly a rare presentation in wildervanck syndrome
topic genu valgum
arachnodactyly
wildervanck syndrome
klippel-feil abnormalities
duane retraction syndrome
url https://ua.ozhurnal.com/index.php/files/article/view/239
work_keys_str_mv AT diptishikhakashyape genuvalgumandarachnodactylyararepresentationinwildervancksyndrome
AT mohitkumar genuvalgumandarachnodactylyararepresentationinwildervancksyndrome