Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions
Background. Procurement of hearts from cardiopulmonary arrest and resuscitated (CPR) donors for transplantation is suboptimal. We studied the influences of donor factors and regional wait times on CPR donor heart utilization. Methods. From UNOS database (1998 to 2012), we identified 44,744 heart don...
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| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2014/519401 |
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| author | Mohammed Quader Luke Wolfe Gundars Katlaps Vigneshwar Kasirajan |
| author_facet | Mohammed Quader Luke Wolfe Gundars Katlaps Vigneshwar Kasirajan |
| author_sort | Mohammed Quader |
| collection | DOAJ |
| description | Background. Procurement of hearts from cardiopulmonary arrest and resuscitated (CPR) donors for transplantation is suboptimal. We studied the influences of donor factors and regional wait times on CPR donor heart utilization. Methods. From UNOS database (1998 to 2012), we identified 44,744 heart donors, of which 4,964 (11%) received CPR. Based on procurement of heart for transplantation, CPR donors were divided into hearts procured (HP) and hearts not procured (HNP) groups. Logistic regression analysis was used to identify predictors of heart procurement. Results. Of the 4,964 CPR donors, 1,427 (28.8%) were in the HP group. Donor characteristics that favored heart procurement include younger age (25.5 ± 15 yrs versus 39 ± 18 yrs, P≤0.0001), male gender (34% versus 23%, P≤0.0001), shorter CPR duration (<15 min versus >30 min, P≤0.0001), and head trauma (60% versus 15%). Among the 11 UNOS regions, the highest procurement was in Region 1 (37%) and the lowest in Region 3 (24%). Regional transplant volumes and median waiting times did not influence heart procurement rates. Conclusions. Only 28.8% of CPR donor hearts were procured for transplantation. Factors favoring heart procurement include younger age, male gender, short CPR duration, and traumatic head injury. Heart procurement varied by region but not by transplant volumes or wait times. |
| format | Article |
| id | doaj-art-aa461ba399d841d19699a5fef0f6799d |
| institution | Kabale University |
| issn | 2090-0007 2090-0015 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Transplantation |
| spelling | doaj-art-aa461ba399d841d19699a5fef0f6799d2025-02-03T01:22:35ZengWileyJournal of Transplantation2090-00072090-00152014-01-01201410.1155/2014/519401519401Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant RegionsMohammed Quader0Luke Wolfe1Gundars Katlaps2Vigneshwar Kasirajan3Department of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA 23298, USADepartment of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA 23298, USABackground. Procurement of hearts from cardiopulmonary arrest and resuscitated (CPR) donors for transplantation is suboptimal. We studied the influences of donor factors and regional wait times on CPR donor heart utilization. Methods. From UNOS database (1998 to 2012), we identified 44,744 heart donors, of which 4,964 (11%) received CPR. Based on procurement of heart for transplantation, CPR donors were divided into hearts procured (HP) and hearts not procured (HNP) groups. Logistic regression analysis was used to identify predictors of heart procurement. Results. Of the 4,964 CPR donors, 1,427 (28.8%) were in the HP group. Donor characteristics that favored heart procurement include younger age (25.5 ± 15 yrs versus 39 ± 18 yrs, P≤0.0001), male gender (34% versus 23%, P≤0.0001), shorter CPR duration (<15 min versus >30 min, P≤0.0001), and head trauma (60% versus 15%). Among the 11 UNOS regions, the highest procurement was in Region 1 (37%) and the lowest in Region 3 (24%). Regional transplant volumes and median waiting times did not influence heart procurement rates. Conclusions. Only 28.8% of CPR donor hearts were procured for transplantation. Factors favoring heart procurement include younger age, male gender, short CPR duration, and traumatic head injury. Heart procurement varied by region but not by transplant volumes or wait times.http://dx.doi.org/10.1155/2014/519401 |
| spellingShingle | Mohammed Quader Luke Wolfe Gundars Katlaps Vigneshwar Kasirajan Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions Journal of Transplantation |
| title | Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions |
| title_full | Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions |
| title_fullStr | Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions |
| title_full_unstemmed | Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions |
| title_short | Donor Heart Utilization following Cardiopulmonary Arrest and Resuscitation: Influence of Donor Characteristics and Wait Times in Transplant Regions |
| title_sort | donor heart utilization following cardiopulmonary arrest and resuscitation influence of donor characteristics and wait times in transplant regions |
| url | http://dx.doi.org/10.1155/2014/519401 |
| work_keys_str_mv | AT mohammedquader donorheartutilizationfollowingcardiopulmonaryarrestandresuscitationinfluenceofdonorcharacteristicsandwaittimesintransplantregions AT lukewolfe donorheartutilizationfollowingcardiopulmonaryarrestandresuscitationinfluenceofdonorcharacteristicsandwaittimesintransplantregions AT gundarskatlaps donorheartutilizationfollowingcardiopulmonaryarrestandresuscitationinfluenceofdonorcharacteristicsandwaittimesintransplantregions AT vigneshwarkasirajan donorheartutilizationfollowingcardiopulmonaryarrestandresuscitationinfluenceofdonorcharacteristicsandwaittimesintransplantregions |