Distinction of IgG4-related mastitis from breast cancer: a case report
Abstract Background Immunoglobulin (Ig) G4-related sclerosing disease is a pathological concept proposed in Japan during the early 2000s. This lesion-forming disease may exhibit characteristics of a systemic disease but often affects a single organ. To date, IgG4-related sclerosing disease in the ma...
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| Format: | Article |
| Language: | English |
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Japan Surgical Society
2019-07-01
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| Series: | Surgical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s40792-019-0681-y |
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| _version_ | 1849407843276423168 |
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| author | Banri Tsuda Nobue Kumaki Rie Ishida Mari Mizuno Kozue Yokoyama Risa Oshitanai Mayako Terao Toru Morioka Takuho Okamura Yuki Saito Yasuhiro Suzuki Naoki Niikura |
| author_facet | Banri Tsuda Nobue Kumaki Rie Ishida Mari Mizuno Kozue Yokoyama Risa Oshitanai Mayako Terao Toru Morioka Takuho Okamura Yuki Saito Yasuhiro Suzuki Naoki Niikura |
| author_sort | Banri Tsuda |
| collection | DOAJ |
| description | Abstract Background Immunoglobulin (Ig) G4-related sclerosing disease is a pathological concept proposed in Japan during the early 2000s. This lesion-forming disease may exhibit characteristics of a systemic disease but often affects a single organ. To date, IgG4-related sclerosing disease in the mammary gland, or IgG4-related mastitis (IgG4-RM), has rarely been reported. Case presentation Here, we describe the case of a female patient who was admitted to our hospital with the main complaints of left breast and axillary lymphadenopathy. A careful diagnostic imaging examination led to an initial suspicion of breast cancer. However, a needle biopsy led to a diagnosis of IgG4-RM. Subsequently, the patient was successfully treated with predonin. Conclusions The treatment requirements for breast cancer and IgG4-RM differ considerably. This is a good example of a case wherein unnecessary surgical treatment, which is indicated for breast cancer, was avoided by needle biopsy. Accordingly, the patient was appropriately treated with steroids following a correct diagnosis. |
| format | Article |
| id | doaj-art-aa46143b52c64e79a56f014304dd92f9 |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2019-07-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-aa46143b52c64e79a56f014304dd92f92025-08-20T03:35:56ZengJapan Surgical SocietySurgical Case Reports2198-77932019-07-01511510.1186/s40792-019-0681-yDistinction of IgG4-related mastitis from breast cancer: a case reportBanri Tsuda0Nobue Kumaki1Rie Ishida2Mari Mizuno3Kozue Yokoyama4Risa Oshitanai5Mayako Terao6Toru Morioka7Takuho Okamura8Yuki Saito9Yasuhiro Suzuki10Naoki Niikura11Department of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Pathology, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University Hachioji HospitalDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineDepartment of Breast and Endocrine Surgery, Tokai University Hachioji HospitalDepartment of Breast and Endocrine Surgery, Tokai University Hachioji HospitalDepartment of Breast and Endocrine Surgery, Tokai University School of MedicineAbstract Background Immunoglobulin (Ig) G4-related sclerosing disease is a pathological concept proposed in Japan during the early 2000s. This lesion-forming disease may exhibit characteristics of a systemic disease but often affects a single organ. To date, IgG4-related sclerosing disease in the mammary gland, or IgG4-related mastitis (IgG4-RM), has rarely been reported. Case presentation Here, we describe the case of a female patient who was admitted to our hospital with the main complaints of left breast and axillary lymphadenopathy. A careful diagnostic imaging examination led to an initial suspicion of breast cancer. However, a needle biopsy led to a diagnosis of IgG4-RM. Subsequently, the patient was successfully treated with predonin. Conclusions The treatment requirements for breast cancer and IgG4-RM differ considerably. This is a good example of a case wherein unnecessary surgical treatment, which is indicated for breast cancer, was avoided by needle biopsy. Accordingly, the patient was appropriately treated with steroids following a correct diagnosis.http://link.springer.com/article/10.1186/s40792-019-0681-yIgG4-related sclerosing diseaseIgG4-related mastitisBreast cancerSteroid therapy |
| spellingShingle | Banri Tsuda Nobue Kumaki Rie Ishida Mari Mizuno Kozue Yokoyama Risa Oshitanai Mayako Terao Toru Morioka Takuho Okamura Yuki Saito Yasuhiro Suzuki Naoki Niikura Distinction of IgG4-related mastitis from breast cancer: a case report Surgical Case Reports IgG4-related sclerosing disease IgG4-related mastitis Breast cancer Steroid therapy |
| title | Distinction of IgG4-related mastitis from breast cancer: a case report |
| title_full | Distinction of IgG4-related mastitis from breast cancer: a case report |
| title_fullStr | Distinction of IgG4-related mastitis from breast cancer: a case report |
| title_full_unstemmed | Distinction of IgG4-related mastitis from breast cancer: a case report |
| title_short | Distinction of IgG4-related mastitis from breast cancer: a case report |
| title_sort | distinction of igg4 related mastitis from breast cancer a case report |
| topic | IgG4-related sclerosing disease IgG4-related mastitis Breast cancer Steroid therapy |
| url | http://link.springer.com/article/10.1186/s40792-019-0681-y |
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