Calcium Mass Balances in Bicarbonate Hemodialysis
Dialysate calcium (Ca) concentration should be viewed as part of the integrated therapeutic regimen to control renal osteodystrophy and maintain normal mineral metabolism. The goals of this integrated approach are to keep the patient in a mild positive Ca mass balance (CaMB), to maintain normal seru...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.4061/2011/540592 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551480979095552 |
|---|---|
| author | Carlo Basile |
| author_facet | Carlo Basile |
| author_sort | Carlo Basile |
| collection | DOAJ |
| description | Dialysate calcium (Ca) concentration should be viewed as part of the integrated therapeutic regimen to control renal osteodystrophy and maintain normal mineral metabolism. The goals of this integrated approach are to keep the patient in a mild positive Ca mass balance (CaMB), to maintain normal serum Ca levels, to control plasma parathyroid hormone values to two to three times above normal levels, and to avoid soft-tissue calcifications. Thus, a correct net CaMB during hemodialysis (HD) is crucial in the treatment of renal osteodystrophy. Very few studies have been published which measured CaMBs in bicarbonate HD. This is mainly due to the technical difficulties in achieving an accurate measurement of CaMBs owing to the need for the collection of the total spent dialysate or of a proportional aliquot of it. Whereas no doubt exists about the fact that an inlet dialysate Ca concentration (CaD) of 1.75 mmol/L leads to a positive CaMB, more controversial is this issue, when dealing with a CaD of 1.50 mmol/L and, even more, when dealing with a CaD of 1.25 mmol/L. Another important issue is the appropriate CaD in long-hour slow-flow nocturnal HD. Finally, which CaMB should we study: ionized CaMB or total CaMB? This issue is largely discussed in the review. |
| format | Article |
| id | doaj-art-aa451314b86f4061821b51d9aa1d253e |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-aa451314b86f4061821b51d9aa1d253e2025-02-03T06:01:20ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/540592540592Calcium Mass Balances in Bicarbonate HemodialysisCarlo Basile0Nephrology and Dialysis Unit, Miulli General Hospital, 70021 Acquaviva delle Fonti, ItalyDialysate calcium (Ca) concentration should be viewed as part of the integrated therapeutic regimen to control renal osteodystrophy and maintain normal mineral metabolism. The goals of this integrated approach are to keep the patient in a mild positive Ca mass balance (CaMB), to maintain normal serum Ca levels, to control plasma parathyroid hormone values to two to three times above normal levels, and to avoid soft-tissue calcifications. Thus, a correct net CaMB during hemodialysis (HD) is crucial in the treatment of renal osteodystrophy. Very few studies have been published which measured CaMBs in bicarbonate HD. This is mainly due to the technical difficulties in achieving an accurate measurement of CaMBs owing to the need for the collection of the total spent dialysate or of a proportional aliquot of it. Whereas no doubt exists about the fact that an inlet dialysate Ca concentration (CaD) of 1.75 mmol/L leads to a positive CaMB, more controversial is this issue, when dealing with a CaD of 1.50 mmol/L and, even more, when dealing with a CaD of 1.25 mmol/L. Another important issue is the appropriate CaD in long-hour slow-flow nocturnal HD. Finally, which CaMB should we study: ionized CaMB or total CaMB? This issue is largely discussed in the review.http://dx.doi.org/10.4061/2011/540592 |
| spellingShingle | Carlo Basile Calcium Mass Balances in Bicarbonate Hemodialysis International Journal of Nephrology |
| title | Calcium Mass Balances in Bicarbonate Hemodialysis |
| title_full | Calcium Mass Balances in Bicarbonate Hemodialysis |
| title_fullStr | Calcium Mass Balances in Bicarbonate Hemodialysis |
| title_full_unstemmed | Calcium Mass Balances in Bicarbonate Hemodialysis |
| title_short | Calcium Mass Balances in Bicarbonate Hemodialysis |
| title_sort | calcium mass balances in bicarbonate hemodialysis |
| url | http://dx.doi.org/10.4061/2011/540592 |
| work_keys_str_mv | AT carlobasile calciummassbalancesinbicarbonatehemodialysis |