Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey

This study sought to determine pesticide residues in some fruits in Tokat province, Turkey and to assess the health risks associated with the determined residues. QuEChERS analytical method was verified to determine 260 pesticides by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). P...

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Main Authors: Kenan Kara, Muammer Kanbolat, Tarık Balkan
Format: Article
Language:English
Published: Ankara University 2023-03-01
Series:Journal of Agricultural Sciences
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Online Access:https://dergipark.org.tr/tr/download/article-file/2452445
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author Kenan Kara
Muammer Kanbolat
Tarık Balkan
author_facet Kenan Kara
Muammer Kanbolat
Tarık Balkan
author_sort Kenan Kara
collection DOAJ
description This study sought to determine pesticide residues in some fruits in Tokat province, Turkey and to assess the health risks associated with the determined residues. QuEChERS analytical method was verified to determine 260 pesticides by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Pesticide solutions corresponded 10 and 50 µg kg­-1 were applied to the pesticide-free apple matrix for the method verification. The linearities (R2), limit of detections, limit of quantifications and mean recovery values of the pesticides ranged between 0.990-0.999, 0.83-3 μg kg­-1, 2.76-9.99 μg kg­-1 and 70.3-119% (with relative standard deviation ≤20%), respectively. The results were evaluated according to the European Union maximum residue limits (EU-MRL). The residues were lower and higher than the EU-MRL with a ratio of 37.7% and 32.1% of the tested samples, respectively. The residue levels of diflubenzuron in apples, permethrin in cherries, and dimethoate in pears, apples, and peaches were higher than the EU-MRL. The results of health risk assessments indicated that omethoate and dimethoate have acute and chronic toxicity potential for consumers. Hence, the pesticide use in the study area must be reduced to avoid health risks. Furthermore, alternative management methods should be developed to lower the use of pesticides.
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publishDate 2023-03-01
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spelling doaj-art-aa4150f13881498cadea152811a1f5b62025-08-20T03:04:11ZengAnkara UniversityJournal of Agricultural Sciences1300-75802148-92972023-03-0129257358810.15832/ankutbd.112253845Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, TurkeyKenan Kara0Muammer Kanbolat1Tarık Balkan2TOKAT GAZIOSMANPASA UNIVERSITY, FACULTY OF AGRICULTUREFmc TurkeyZİRAAT FAKÜLTESİThis study sought to determine pesticide residues in some fruits in Tokat province, Turkey and to assess the health risks associated with the determined residues. QuEChERS analytical method was verified to determine 260 pesticides by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Pesticide solutions corresponded 10 and 50 µg kg­-1 were applied to the pesticide-free apple matrix for the method verification. The linearities (R2), limit of detections, limit of quantifications and mean recovery values of the pesticides ranged between 0.990-0.999, 0.83-3 μg kg­-1, 2.76-9.99 μg kg­-1 and 70.3-119% (with relative standard deviation ≤20%), respectively. The results were evaluated according to the European Union maximum residue limits (EU-MRL). The residues were lower and higher than the EU-MRL with a ratio of 37.7% and 32.1% of the tested samples, respectively. The residue levels of diflubenzuron in apples, permethrin in cherries, and dimethoate in pears, apples, and peaches were higher than the EU-MRL. The results of health risk assessments indicated that omethoate and dimethoate have acute and chronic toxicity potential for consumers. Hence, the pesticide use in the study area must be reduced to avoid health risks. Furthermore, alternative management methods should be developed to lower the use of pesticides.https://dergipark.org.tr/tr/download/article-file/2452445lc-ms/msfresh fruitmethod verificationhealth riskquechers
spellingShingle Kenan Kara
Muammer Kanbolat
Tarık Balkan
Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
Journal of Agricultural Sciences
lc-ms/ms
fresh fruit
method verification
health risk
quechers
title Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
title_full Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
title_fullStr Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
title_full_unstemmed Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
title_short Verification of QuEChERS Method for the Analysis of Pesticide Residues and Their Risk Assessment in Some Fruits Grown in Tokat, Turkey
title_sort verification of quechers method for the analysis of pesticide residues and their risk assessment in some fruits grown in tokat turkey
topic lc-ms/ms
fresh fruit
method verification
health risk
quechers
url https://dergipark.org.tr/tr/download/article-file/2452445
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AT muammerkanbolat verificationofquechersmethodfortheanalysisofpesticideresiduesandtheirriskassessmentinsomefruitsgrownintokatturkey
AT tarıkbalkan verificationofquechersmethodfortheanalysisofpesticideresiduesandtheirriskassessmentinsomefruitsgrownintokatturkey