Efficacy and Safety of Intravenous Thrombolysis Beyond 4.5 Hours in Ischemic Stroke: A Systematic Review and Meta-Analysis

Efficacy and Safety of Intravenous Thrombolysis Beyond 4.5 Hours in Ischemic Stroke: A Systematic Review and Meta-Analysis

<b>Background</b>: Intravenous thrombolysis (IVT) is the standard treatment for ischemic stroke within 4.5 h of symptom onset. However, a significant proportion of patients present beyond this window. This study aims to evaluate the efficacy and safety of IVT beyond the 4.5 h window in s...

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Main Authors: Muhammad Ahmad, Chavin Akalanka Ranasinghe, Mais Omar Abu-Sa’da, Durga Prasad Bhimineni, Muhammed Ameen Noushad, Talal Warsi, Ahmad Mesmar, Munikaverappa Anjanappa Mukesh, Sagar K. Patel, Gabriel Imbianozor, Ali Mustansir Bhatty, Ahmad Alareed, Quratul Ain, Eeshal Zulfiqar, Mushood Ahmed, Raheel Ahmed
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
ischemic stroke
thrombolysis
tenecteplase
alteplase
meta-analysis
Online Access:https://www.mdpi.com/2075-4418/15/14/1812
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