Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms

Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms

Abstract Accurately identification of cyclin-dependent kinase inhibitor 2A (CDKN2A) status is of paramount important, as it has been reported as an unfavorable prognostic biomarker in diffuse gliomas, both IDH-mutant and IDH-wild type. Various methods are available for identifying CDKN2A deletion, w...

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Bibliographic Details
Main Authors: Hainan Li, Ningning Luo, Chongzhu Fan, Tiantian Han, Xuemin Wei, Xing Zhang, Lijun Dai, Lei Ye, Dongsheng Chen, Linbo Cai, Zhi Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Cancer
Subjects:
Gliomas
CDKN2A deletion
NGS
FISH
Multiple detection platforms
Online Access:https://doi.org/10.1186/s12885-025-14266-x
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