Application of video surveillance in preclinical safety studies in canines: Understanding the interobserver reliability and validity to recognize clinical behavior.

Application of video surveillance in preclinical safety studies in canines: Understanding the interobserver reliability and validity to recognize clinical behavior.

Preclinical in vivo studies are critical to identify potential adverse effects of drugs under development. However, a significant number of drug candidates are terminated during human clinical trials due to unexpected adverse events which were not predicted or detected in preclinical studies. Video...

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Bibliographic Details
Main Authors: Eline Eberhardt, Fetene Tekle, Greet Teuns, Jill Witters, Bianca Feyen, Sarah De Landtsheer, Ivan Kopljar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326916
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