Efficacy and safety of PD-1/PD-L1 inhibitors in patients with Merkel Cell Carcinoma: a systematic review and Meta-analysis

Efficacy and safety of PD-1/PD-L1 inhibitors in patients with Merkel Cell Carcinoma: a systematic review and Meta-analysis

Abstract Background Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer characterized by high rates of metastasis. Emerging evidence suggests that PD-L1/PD1 blockade holds promise as a therapeutic option for MCC. However, the efficacy and safety of this approach in treati...

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Bibliographic Details
Main Authors: Francisco Cezar Aquino de Moraes, Michele Kreuz, Isabella Christina Amaral de Lara, Artur de Oliveira Macena Lôbo, Rommel Mario Rodríguez Burbano
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Merkel cell carcinoma
Skin cancer
PD-1/PD-L1 inhibitors
Meta-analysis
Online Access:https://doi.org/10.1186/s12885-024-13129-1
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