The effect of blood transfusion on serum hepcidin levels in chronically transfused patients of β-thalassemia major: An observational study in a tertiary care centre in Western Maharashtra

The effect of blood transfusion on serum hepcidin levels in chronically transfused patients of β-thalassemia major: An observational study in a tertiary care centre in Western Maharashtra

INTRODUCTION: Hepcidin is the key regulator of systemic iron homeostasis. In iron-loading anemias, hepcidin levels are regulated by opposite forces of erythropoiesis and iron overload. In β-thalassemia major patients, transfusions are the predominant cause of iron overload; in such chronically trans...

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Bibliographic Details
Main Authors: Sujay Bhowmik, Amit Kumar Biswas, Ajay Kumar Baranwal, Amit Ajay Pawar, Ujjwal Dimri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Asian Journal of Transfusion Science
Subjects:
β-thalassemia major
hepcidin
iron overload
transfusion-dependent thalassemia
Online Access:https://journals.lww.com/10.4103/ajts.ajts_160_22
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