Multi-Algorithm-Integrated Tertiary Lymphoid Structure Gene Signature for Immune Landscape Characterization and Prognosis in Colorectal Cancer Patients

Multi-Algorithm-Integrated Tertiary Lymphoid Structure Gene Signature for Immune Landscape Characterization and Prognosis in Colorectal Cancer Patients

Purpose: Colorectal cancer (CRC) is a common malignancy with a low survival rate as well as a low response rate to immunotherapy. This study aims to develop a risk model based on tertiary lymphoid structure (TLS)-associated gene signatures to enhance predictions of prognosis and immunotherapy respon...

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Bibliographic Details
Main Authors: Xianqiang Liu, Dingchang Li, Yue Zhang, Hao Liu, Peng Chen, Yingjie Zhao, Guanchao Sun, Wen Zhao, Guanglong Dong
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
immune cell infiltration
bioinformatics analysis
consensus clustering
immunotherapy
tumor microenvironment
machine learning
Online Access:https://www.mdpi.com/2227-9059/12/11/2644
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