Perillaldehyde synergizes with ferroptosis inducers to promote ferroptotic cell death in gastric cancer

Perillaldehyde synergizes with ferroptosis inducers to promote ferroptotic cell death in gastric cancer

IntroductionAs a traditional medicine and food homologous plant, Perilla frutescens is widely cultivated in China, Japan, and Korea. According to the Compendium of Materia Medica, the leaves, stems, and seeds of perilla can all be used as medicine. Perilla essential oil has been used in traditional...

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Main Authors: Rui Wang, Jin-Feng Cui, Jing Lv, Jia-Lin Song, Yang-Yang Lu, Xiao-Juan Huang, Zhong-Kun Lin, Si-Yi Zhang, Sha-Sha Wang, Wen-Sheng Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
natural products
perillaldehyde
gastric cancer
oxidative stress
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1598520/full
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