SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION

The study evaluated the efficacy of reamberin in complex treatment of patients with acute small bowel obstruction. Methods. The research is based on the results of complex examination of 202 patients with acute small bowel obstruction (ASBO). The patients were hospitalized in Ivano-Frankovsk central...

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Main Authors: V. D. Skripko, A. L. Kovalenko, V. A. Zaplutanov
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2017-02-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/300
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author V. D. Skripko
A. L. Kovalenko
V. A. Zaplutanov
author_facet V. D. Skripko
A. L. Kovalenko
V. A. Zaplutanov
author_sort V. D. Skripko
collection DOAJ
description The study evaluated the efficacy of reamberin in complex treatment of patients with acute small bowel obstruction. Methods. The research is based on the results of complex examination of 202 patients with acute small bowel obstruction (ASBO). The patients were hospitalized in Ivano-Frankovsk central municipal clinical hospital at the period from 2009 to 2015. The patients were divided into two groups according to the method of treatment. The complex treatment using common method was applied for the first group of 100 patients with ASBO. The complex treatment using common method and reamberin intravenously (800 ml/day) during 7 days was applied for the second group of 102 patients. Results. The application of reamberin reduced a lot of indices such as leukocytic intoxication, intoxication index, level of middle mass molecule, formation of malonic dialdehyde. The drug stimulated antioxidant system and normalized organ-specific liver enzymes. Conclusions. The application of reamberin is pathogenetically validated in cases of ASBO.
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issn 0042-4625
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publisher Pavlov First Saint Petersburg State Medical University
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series Вестник хирургии имени И.И. Грекова
spelling doaj-art-aa0e686692634400b2160ab95e4b335f2025-08-20T03:02:11ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252017-02-011761808610.24884/0042-4625-2017-176-1-80-86299SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTIONV. D. Skripko0A. L. Kovalenko1V. A. Zaplutanov2Ivano-Frankovsk National Medical UniversityInstitute of Toxicology of Federal Biomedical AgencySaint-Petersburg State Chemical-Pharmaceutical AcademyThe study evaluated the efficacy of reamberin in complex treatment of patients with acute small bowel obstruction. Methods. The research is based on the results of complex examination of 202 patients with acute small bowel obstruction (ASBO). The patients were hospitalized in Ivano-Frankovsk central municipal clinical hospital at the period from 2009 to 2015. The patients were divided into two groups according to the method of treatment. The complex treatment using common method was applied for the first group of 100 patients with ASBO. The complex treatment using common method and reamberin intravenously (800 ml/day) during 7 days was applied for the second group of 102 patients. Results. The application of reamberin reduced a lot of indices such as leukocytic intoxication, intoxication index, level of middle mass molecule, formation of malonic dialdehyde. The drug stimulated antioxidant system and normalized organ-specific liver enzymes. Conclusions. The application of reamberin is pathogenetically validated in cases of ASBO.https://www.vestnik-grekova.ru/jour/article/view/300acute small bowel obstructionendogenous intoxicationreamberin
spellingShingle V. D. Skripko
A. L. Kovalenko
V. A. Zaplutanov
SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
Вестник хирургии имени И.И. Грекова
acute small bowel obstruction
endogenous intoxication
reamberin
title SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
title_full SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
title_fullStr SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
title_full_unstemmed SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
title_short SUBSTANTIATION OF REAMBERIN APPLICATION IN COMPLEX TREATMENT OF PATIENTS WITH ACUTE SMALL BOWEL OBSTRUCTION
title_sort substantiation of reamberin application in complex treatment of patients with acute small bowel obstruction
topic acute small bowel obstruction
endogenous intoxication
reamberin
url https://www.vestnik-grekova.ru/jour/article/view/300
work_keys_str_mv AT vdskripko substantiationofreamberinapplicationincomplextreatmentofpatientswithacutesmallbowelobstruction
AT alkovalenko substantiationofreamberinapplicationincomplextreatmentofpatientswithacutesmallbowelobstruction
AT vazaplutanov substantiationofreamberinapplicationincomplextreatmentofpatientswithacutesmallbowelobstruction