Immune counter-evolution: immortalized B cell clones can undergo ex vivo directed evolution to counteract viral escape
IntroductionAmid the persistent threat of future pandemics, the continuous evolution of SARS-CoV-2 exposed critical challenges for vaccine efficacy and therapeutic interventions, highlighting the need for rapid and adaptable approaches to respond to immune escape variants.MethodsHere, we report the...
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| Main Authors: | Casper Marsman, Jurgen Heinen, Vanessa Clerico Mosina, Kelly Maijoor, Arjen Q. Bakker, Michael Koslowski, Alessandra Villa, Stefano Gullà |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1648717/full |
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