FUNCTIONAL ACTIVITY OF ANTI-GD2 CAR-T CELLS WITH DIFFERENT ANTIGEN-RECOGNITION MODULE
AbstractNeuroblastoma (NB) is the most common extracranial solid tumor in children, 8-10% of all pediatric tumors and an incidence of about 1-1.3 cases per 100,000 children under 15 years of age. Despite the use of intensive treatment with surgery, high-dose chemotherapy and radiotherapy, the 5-year...
Saved in:
| Main Authors: | Dzmitry Lutskovich, Hanna Klych, Maryia Maryia A. Keraz, Kate Lutskovich, Alexander Meleshko |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2019-08-01
|
| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/3161 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
GD2 targeting CAR T cells for neuroblastoma
by: John Anderson, et al.
Published: (2024-12-01) -
Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells
by: Michele Pezzella, et al.
Published: (2024-12-01) -
Inhibition of autophagy enhances the antitumor efficacy of T/CAR T cell against neuroblastoma
by: Francesca De Mitri, et al.
Published: (2025-07-01) -
The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1
by: Adeiye A. Pilgrim, et al.
Published: (2023-12-01) -
Preliminary exploration of PSMA CAR-T combined with GD2 CAR-T for the treatment of refractory/relapsed gliomas
by: Jinshan Gu, et al.
Published: (2025-05-01)