Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome
Aim: The aim of this study was to compare initial and final exercise tolerance and to evaluate the determinants of exercise capacity improvement—after three weeks of inpatient cardiac rehabilitation. Methods: A cohort of 494 patients after acute coronary syndrome (ACS), treated with primary coronary...
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| Format: | Article |
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Open Exploration Publishing Inc.
2023-08-01
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| Series: | Exploration of Cardiology |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A10124/10124.pdf |
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| author | Barbara Uznańska-Loch Ewa Wądołowska Karina Wierzbowska-Drabik Urszula Cieślik-Guerra Jarosław D. Kasprzak Małgorzata Kurpesa Tomasz Rechciński |
| author_facet | Barbara Uznańska-Loch Ewa Wądołowska Karina Wierzbowska-Drabik Urszula Cieślik-Guerra Jarosław D. Kasprzak Małgorzata Kurpesa Tomasz Rechciński |
| author_sort | Barbara Uznańska-Loch |
| collection | DOAJ |
| description | Aim: The aim of this study was to compare initial and final exercise tolerance and to evaluate the determinants of exercise capacity improvement—after three weeks of inpatient cardiac rehabilitation. Methods: A cohort of 494 patients after acute coronary syndrome (ACS), treated with primary coronary angioplasty (age 60 years ± 10 years, 27.5% women) was studied retrospectively. Possible correlations between improvement and age, gender, body mass index (BMI), left ventricular ejection fraction (LVEF) and the initial exercise capacity (EXT1) were assessed. Results: The highest percentage of patients with improvement (43.6%) was in the medium tercile of LVEF (> 42% but ≤ 50%) and was more likely in the medium tercile of initial exercise tolerance [> 5.7 but ≤ 8.4 metabolic equivalent of tasks (METs)]. Receiver-operator characteristic (ROC) curves were developed and the following cut-off values were found: for LVEF > 43% (this value had 69.6% sensitivity in predicting improvement; the chance of improvement was 2.67 higher than in patients with LVEF ≤ 43%); for EXT1 ≤ 8.4 METs (this value had 70.8% sensitivity, the chance of improvement was 1.86 higher than in the other subgroup). No significant relationship between improvement and gender, age or BMI was found. Conclusions: The combination of LVEF > 43% and EXT1 ≤ 8.4 METs relates to the highest probability of exercise tolerance improvement after cardiac rehabilitation. |
| format | Article |
| id | doaj-art-a9e9332944b4467cb0ce7085f9397fdf |
| institution | Kabale University |
| issn | 2994-5526 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Cardiology |
| spelling | doaj-art-a9e9332944b4467cb0ce7085f9397fdf2025-08-20T03:50:31ZengOpen Exploration Publishing Inc.Exploration of Cardiology2994-55262023-08-0111263410.37349/ec.2023.00004Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndromeBarbara Uznańska-Loch0Ewa Wądołowska1Karina Wierzbowska-Drabik2https://orcid.org/0000-0002-7623-5389Urszula Cieślik-Guerra3https://orcid.org/0000-0001-6297-2153Jarosław D. Kasprzak4https://orcid.org/0000-0002-5850-8187Małgorzata Kurpesa5https://orcid.org/0000-0002-8194-0285Tomasz Rechciński6https://orcid.org/0000-0001-7800-785XChair and Department of Cardiology, Medical University of Lodz, 91-347 Lodz, PolandDepartment of Cardiac Rehabilitation, The Biegański Hospital, 91-347 Lodz, PolandDepartment of Internal Diseases and Clinical Pharmacology, Medical University of Lodz, 91-347 Lodz, PolandDepartment of Cardiac Rehabilitation, The Biegański Hospital, 91-347 Lodz, PolandChair and Department of Cardiology, Medical University of Lodz, 91-347 Lodz, PolandChair and Department of Cardiology, Medical University of Lodz, 91-347 Lodz, PolandChair and Department of Cardiology, Medical University of Lodz, 91-347 Lodz, PolandAim: The aim of this study was to compare initial and final exercise tolerance and to evaluate the determinants of exercise capacity improvement—after three weeks of inpatient cardiac rehabilitation. Methods: A cohort of 494 patients after acute coronary syndrome (ACS), treated with primary coronary angioplasty (age 60 years ± 10 years, 27.5% women) was studied retrospectively. Possible correlations between improvement and age, gender, body mass index (BMI), left ventricular ejection fraction (LVEF) and the initial exercise capacity (EXT1) were assessed. Results: The highest percentage of patients with improvement (43.6%) was in the medium tercile of LVEF (> 42% but ≤ 50%) and was more likely in the medium tercile of initial exercise tolerance [> 5.7 but ≤ 8.4 metabolic equivalent of tasks (METs)]. Receiver-operator characteristic (ROC) curves were developed and the following cut-off values were found: for LVEF > 43% (this value had 69.6% sensitivity in predicting improvement; the chance of improvement was 2.67 higher than in patients with LVEF ≤ 43%); for EXT1 ≤ 8.4 METs (this value had 70.8% sensitivity, the chance of improvement was 1.86 higher than in the other subgroup). No significant relationship between improvement and gender, age or BMI was found. Conclusions: The combination of LVEF > 43% and EXT1 ≤ 8.4 METs relates to the highest probability of exercise tolerance improvement after cardiac rehabilitation.https://www.explorationpub.com/uploads/Article/A10124/10124.pdfcardiac rehabilitationacute coronary syndromeejection fractionexercise capacity |
| spellingShingle | Barbara Uznańska-Loch Ewa Wądołowska Karina Wierzbowska-Drabik Urszula Cieślik-Guerra Jarosław D. Kasprzak Małgorzata Kurpesa Tomasz Rechciński Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome Exploration of Cardiology cardiac rehabilitation acute coronary syndrome ejection fraction exercise capacity |
| title | Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome |
| title_full | Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome |
| title_fullStr | Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome |
| title_full_unstemmed | Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome |
| title_short | Left ventricular systolic function and initial exercise capacity—their importance for results of cardiac rehabilitation after acute coronary syndrome |
| title_sort | left ventricular systolic function and initial exercise capacity their importance for results of cardiac rehabilitation after acute coronary syndrome |
| topic | cardiac rehabilitation acute coronary syndrome ejection fraction exercise capacity |
| url | https://www.explorationpub.com/uploads/Article/A10124/10124.pdf |
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