Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features

Lumen segmentation in intravascular optical coherence tomography (IVOCT) images is a fundamental work for more advanced plaque analysis, stent recognition, fractional flow reserve (FFR) assessment, and so on. However, the catheter, guide-wire, inadequate blood clearance, and other factors will impac...

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Main Authors: Huishuo Zhao, Bin He, Zhenyang Ding, Kuiyuan Tao, Tianduo Lai, Hao Kuang, Rui Liu, Xiaoguo Zhang, Yicheng Zheng, Junyi Zheng, Tiegen Liu
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/8752356/
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author Huishuo Zhao
Bin He
Zhenyang Ding
Kuiyuan Tao
Tianduo Lai
Hao Kuang
Rui Liu
Xiaoguo Zhang
Yicheng Zheng
Junyi Zheng
Tiegen Liu
author_facet Huishuo Zhao
Bin He
Zhenyang Ding
Kuiyuan Tao
Tianduo Lai
Hao Kuang
Rui Liu
Xiaoguo Zhang
Yicheng Zheng
Junyi Zheng
Tiegen Liu
author_sort Huishuo Zhao
collection DOAJ
description Lumen segmentation in intravascular optical coherence tomography (IVOCT) images is a fundamental work for more advanced plaque analysis, stent recognition, fractional flow reserve (FFR) assessment, and so on. However, the catheter, guide-wire, inadequate blood clearance, and other factors will impact on the accuracy of lumen segmentation. We present a simple and effective method for automatic lumen segmentation method in IVOCT based on morphological features. We use image enhancement, median filtering, image binarization, and morphological closing operation to reduce speckle noise, minimize the effect of blood artifacts and fill in small holes inside vascular walls. We extract the orientation and area-size of connected regions as morphological features in images and remove the catheter and guide-wire completely by morphological corrosion operation, small area-size region removal, and orientation morphological feature comparison, and then the contour of the lumen can be discriminated. The evaluation metrics of this method, the Dice index, Hausdorff distance, Jaccard index, and accuracy of 99.32%, 0.06 mm, 99.4%, and 99.66%, respectively, are obtained from comparing with expert annotations on 268 IVOCT images. Compared with the other morphology-based lumen segmentation methods, the presented method can remove the catheter and guide-wire completely, even if the catheter and guide-wire cling to the lumen or the shape of the catheter is irregular. Since only morphological operations are used to complete all processes, the calculation burden is reduced greatly.
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spelling doaj-art-a9e581e1c96d4bcdab9a0be8e81e08842025-08-20T03:13:42ZengIEEEIEEE Access2169-35362019-01-017888598886910.1109/ACCESS.2019.29259178752356Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological FeaturesHuishuo Zhao0Bin He1Zhenyang Ding2https://orcid.org/0000-0002-0483-477XKuiyuan Tao3Tianduo Lai4Hao Kuang5Rui Liu6Xiaoguo Zhang7Yicheng Zheng8Junyi Zheng9Tiegen Liu10School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaNanjing Forssmann Medical Technology Company, Nanjing, ChinaDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaSchool of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin, ChinaLumen segmentation in intravascular optical coherence tomography (IVOCT) images is a fundamental work for more advanced plaque analysis, stent recognition, fractional flow reserve (FFR) assessment, and so on. However, the catheter, guide-wire, inadequate blood clearance, and other factors will impact on the accuracy of lumen segmentation. We present a simple and effective method for automatic lumen segmentation method in IVOCT based on morphological features. We use image enhancement, median filtering, image binarization, and morphological closing operation to reduce speckle noise, minimize the effect of blood artifacts and fill in small holes inside vascular walls. We extract the orientation and area-size of connected regions as morphological features in images and remove the catheter and guide-wire completely by morphological corrosion operation, small area-size region removal, and orientation morphological feature comparison, and then the contour of the lumen can be discriminated. The evaluation metrics of this method, the Dice index, Hausdorff distance, Jaccard index, and accuracy of 99.32%, 0.06 mm, 99.4%, and 99.66%, respectively, are obtained from comparing with expert annotations on 268 IVOCT images. Compared with the other morphology-based lumen segmentation methods, the presented method can remove the catheter and guide-wire completely, even if the catheter and guide-wire cling to the lumen or the shape of the catheter is irregular. Since only morphological operations are used to complete all processes, the calculation burden is reduced greatly.https://ieeexplore.ieee.org/document/8752356/Optical coherence tomographyintravascular optical coherence tomographyimage segmentationmorphological operationlumen segmentation
spellingShingle Huishuo Zhao
Bin He
Zhenyang Ding
Kuiyuan Tao
Tianduo Lai
Hao Kuang
Rui Liu
Xiaoguo Zhang
Yicheng Zheng
Junyi Zheng
Tiegen Liu
Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
IEEE Access
Optical coherence tomography
intravascular optical coherence tomography
image segmentation
morphological operation
lumen segmentation
title Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
title_full Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
title_fullStr Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
title_full_unstemmed Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
title_short Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Using Morphological Features
title_sort automatic lumen segmentation in intravascular optical coherence tomography using morphological features
topic Optical coherence tomography
intravascular optical coherence tomography
image segmentation
morphological operation
lumen segmentation
url https://ieeexplore.ieee.org/document/8752356/
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