PROGNOSTICATION OF VACCINATION EFFICACY
The article focuses on the study of protective immunity in vaccination with pneumococcal conjugated 7-valent vaccine (PCV7) against related vaccine serotypes. It provides results of a study which compared the opsonization capability of all vaccine serotypes with that of two related serotypes (6A and...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Union of pediatricians of Russia
2010-03-01
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| Series: | Педиатрическая фармакология |
| Online Access: | https://www.pedpharma.ru/jour/article/view/1165 |
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| _version_ | 1849244071734804480 |
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| author | N.F. Snegova S.M. Kharit V.K. Tatochenko M.P. Kostinov |
| author_facet | N.F. Snegova S.M. Kharit V.K. Tatochenko M.P. Kostinov |
| author_sort | N.F. Snegova |
| collection | DOAJ |
| description | The article focuses on the study of protective immunity in vaccination with pneumococcal conjugated 7-valent vaccine (PCV7) against related vaccine serotypes. It provides results of a study which compared the opsonization capability of all vaccine serotypes with that of two related serotypes (6A and 19A) to analyse immune response. The study results showed that functional cross immunity to serotype 19A after vaccination with conjugated vaccine that does not contain polysaccharide of this serotype is virtually non-existent. Key words: invasive pneumococcal infections, pneumococcal conjugated 7-valent vaccine, children, related vaccine serotypes, opsonophagocytic activity. (Pediatric Pharmacology. – 2010; 7(2):36-40) |
| format | Article |
| id | doaj-art-a9e092d29ca846a8be4ff677f665c773 |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2010-03-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-a9e092d29ca846a8be4ff677f665c7732025-08-20T03:59:16ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892010-03-017236401160PROGNOSTICATION OF VACCINATION EFFICACYN.F. Snegova0S.M. Kharit1V.K. Tatochenko2M.P. Kostinov3FSI RI of Immunology and Allergology of Russia’s Federal Medical and Biological Agency, MoscowFSI RI of Children’s Infections of Russia’s Federal Medical and Biological Agency, Saint-PetersburgScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowFSI RI of Vaccines and Sera named after I.I. Mechnikov, MoscowThe article focuses on the study of protective immunity in vaccination with pneumococcal conjugated 7-valent vaccine (PCV7) against related vaccine serotypes. It provides results of a study which compared the opsonization capability of all vaccine serotypes with that of two related serotypes (6A and 19A) to analyse immune response. The study results showed that functional cross immunity to serotype 19A after vaccination with conjugated vaccine that does not contain polysaccharide of this serotype is virtually non-existent. Key words: invasive pneumococcal infections, pneumococcal conjugated 7-valent vaccine, children, related vaccine serotypes, opsonophagocytic activity. (Pediatric Pharmacology. – 2010; 7(2):36-40)https://www.pedpharma.ru/jour/article/view/1165 |
| spellingShingle | N.F. Snegova S.M. Kharit V.K. Tatochenko M.P. Kostinov PROGNOSTICATION OF VACCINATION EFFICACY Педиатрическая фармакология |
| title | PROGNOSTICATION OF VACCINATION EFFICACY |
| title_full | PROGNOSTICATION OF VACCINATION EFFICACY |
| title_fullStr | PROGNOSTICATION OF VACCINATION EFFICACY |
| title_full_unstemmed | PROGNOSTICATION OF VACCINATION EFFICACY |
| title_short | PROGNOSTICATION OF VACCINATION EFFICACY |
| title_sort | prognostication of vaccination efficacy |
| url | https://www.pedpharma.ru/jour/article/view/1165 |
| work_keys_str_mv | AT nfsnegova prognosticationofvaccinationefficacy AT smkharit prognosticationofvaccinationefficacy AT vktatochenko prognosticationofvaccinationefficacy AT mpkostinov prognosticationofvaccinationefficacy |