Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes
Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on tw...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/891342 |
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| _version_ | 1849396980666597376 |
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| author | Chris M. Cirimotich April M. Clayton George Dimopoulos |
| author_facet | Chris M. Cirimotich April M. Clayton George Dimopoulos |
| author_sort | Chris M. Cirimotich |
| collection | DOAJ |
| description | Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches. |
| format | Article |
| id | doaj-art-a9db5fa28fb346f5a0897570bd3680f0 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-a9db5fa28fb346f5a0897570bd3680f02025-08-20T03:39:10ZengWileyJournal of Tropical Medicine1687-96861687-96942011-01-01201110.1155/2011/891342891342Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles MosquitoesChris M. Cirimotich0April M. Clayton1George Dimopoulos2W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USAW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USAW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USACurrent efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.http://dx.doi.org/10.1155/2011/891342 |
| spellingShingle | Chris M. Cirimotich April M. Clayton George Dimopoulos Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes Journal of Tropical Medicine |
| title | Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes |
| title_full | Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes |
| title_fullStr | Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes |
| title_full_unstemmed | Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes |
| title_short | Low- and High-Tech Approaches to Control Plasmodium Parasite Transmission by Anopheles Mosquitoes |
| title_sort | low and high tech approaches to control plasmodium parasite transmission by anopheles mosquitoes |
| url | http://dx.doi.org/10.1155/2011/891342 |
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