NEO adjuvant chemotherapy in breast cancer: What have we learned so far?
Neoadjuvant chemotherapy (NACT) in breast cancer has undergone continuous evolution over the last few decades to establish its role in the combined modality management of these tumors. The process of evolution is still far from over. Many questions are still lurking in the minds of oncologists treat...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2010-03-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
| Subjects: | |
| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2010;volume=31;issue=1;spage=8;epage=17;aulast=Raut |
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| _version_ | 1849739620657397760 |
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| author | Raut Nirmal Chordiya Nilesh |
| author_facet | Raut Nirmal Chordiya Nilesh |
| author_sort | Raut Nirmal |
| collection | DOAJ |
| description | Neoadjuvant chemotherapy (NACT) in breast cancer has undergone continuous evolution over the last few decades to establish its role in the combined modality management of these tumors. The process of evolution is still far from over. Many questions are still lurking in the minds of oncologists treating breast cancer. This review analyzes the evidence from metaanlyses, major multiinstitutional prospective trials, retrospective institutional series and systematic reviews in breast cancer to determine the current standards and controversies in NACT. The most effective drugs, their advantages, issues and controversies in delivery as well as the criteria for response are reviewed. A summary of evidence-based consensus is presented and unresolved aspects are discussed. |
| format | Article |
| id | doaj-art-a9d58ba7d31b414bbb4d9645a1b7345e |
| institution | DOAJ |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2010-03-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-a9d58ba7d31b414bbb4d9645a1b7345e2025-08-20T03:06:13ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292010-03-01311817NEO adjuvant chemotherapy in breast cancer: What have we learned so far?Raut NirmalChordiya NileshNeoadjuvant chemotherapy (NACT) in breast cancer has undergone continuous evolution over the last few decades to establish its role in the combined modality management of these tumors. The process of evolution is still far from over. Many questions are still lurking in the minds of oncologists treating breast cancer. This review analyzes the evidence from metaanlyses, major multiinstitutional prospective trials, retrospective institutional series and systematic reviews in breast cancer to determine the current standards and controversies in NACT. The most effective drugs, their advantages, issues and controversies in delivery as well as the criteria for response are reviewed. A summary of evidence-based consensus is presented and unresolved aspects are discussed.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2010;volume=31;issue=1;spage=8;epage=17;aulast=Raut<i>Breast cancerneoadjuvant chemotherapyreview</i> |
| spellingShingle | Raut Nirmal Chordiya Nilesh NEO adjuvant chemotherapy in breast cancer: What have we learned so far? Indian Journal of Medical and Paediatric Oncology <i>Breast cancer neoadjuvant chemotherapy review</i> |
| title | NEO adjuvant chemotherapy in breast cancer: What have we learned so far? |
| title_full | NEO adjuvant chemotherapy in breast cancer: What have we learned so far? |
| title_fullStr | NEO adjuvant chemotherapy in breast cancer: What have we learned so far? |
| title_full_unstemmed | NEO adjuvant chemotherapy in breast cancer: What have we learned so far? |
| title_short | NEO adjuvant chemotherapy in breast cancer: What have we learned so far? |
| title_sort | neo adjuvant chemotherapy in breast cancer what have we learned so far |
| topic | <i>Breast cancer neoadjuvant chemotherapy review</i> |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2010;volume=31;issue=1;spage=8;epage=17;aulast=Raut |
| work_keys_str_mv | AT rautnirmal neoadjuvantchemotherapyinbreastcancerwhathavewelearnedsofar AT chordiyanilesh neoadjuvantchemotherapyinbreastcancerwhathavewelearnedsofar |