Chromatin-based memory as a self-stabilizing influence on cell identity
Abstract Cell types are traditionally thought to be specified and stabilized by gene regulatory networks. Here, we explore how chromatin memory contributes to the specification and stabilization of cell states. Through pervasive, local, feedback loops, chromatin memory enables cell states that were...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-024-03461-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|