CD56bright cytokine-induced memory-like NK cells and NK-cell engagers synergize against non-small cell lung cancer cancer-stem cells

CD56bright cytokine-induced memory-like NK cells and NK-cell engagers synergize against non-small cell lung cancer cancer-stem cells

Background Due to their enhanced responsiveness and persistence, cytokine-induced memory-like (CIML)-natural killer (NK) cells have emerged as new immunotherapeutic tools against malignancies. However, their effects on tumor-cell spread and metastases in solid tumors remain poorly investigated. More...

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Main Authors: Paola Orecchia, Maria Cristina Mingari, Martin Felices, Monica Parodi, Luca Roz, Massimo Vitale, Giulia Bertolini, Claudia Cantoni, Maria L Guevara Lopez, Ann Gebo, Stefano Persano, Josephine Maus-Conn, Fabrizio Loiacono, Simona Sivori, Marco Gentili, Federica Facchinetti, Riccardo Ferracini, Daniel A Vallera, Marco Pravetoni
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/2/e010205.full
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