Bendamustine Associated with Irreversible Ascending Paralysis

Bendamustine is an alkylating agent currently used in the treatment of lymphoproliferative disorders. Many adverse effects, including a rare case of reversible neurotoxicity, have been reported in association with bendamustine. Herein, we report the first case of irreversible ascending paralysis rel...

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Main Authors: Ashraf Alhafez, Omar S. Aljitawi, Tara L. Lin, Siddhartha Ganguly, Sunil Abhyankar, Joseph P. McGuirk
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2013/931519
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author Ashraf Alhafez
Omar S. Aljitawi
Tara L. Lin
Siddhartha Ganguly
Sunil Abhyankar
Joseph P. McGuirk
author_facet Ashraf Alhafez
Omar S. Aljitawi
Tara L. Lin
Siddhartha Ganguly
Sunil Abhyankar
Joseph P. McGuirk
author_sort Ashraf Alhafez
collection DOAJ
description Bendamustine is an alkylating agent currently used in the treatment of lymphoproliferative disorders. Many adverse effects, including a rare case of reversible neurotoxicity, have been reported in association with bendamustine. Herein, we report the first case of irreversible ascending paralysis related to bendamustine.
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id doaj-art-a9c95fe3e8bf4f1d82c7bbc47f54d8b7
institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-a9c95fe3e8bf4f1d82c7bbc47f54d8b72025-02-03T05:44:56ZengWileyCase Reports in Hematology2090-65602090-65792013-01-01201310.1155/2013/931519931519Bendamustine Associated with Irreversible Ascending ParalysisAshraf Alhafez0Omar S. Aljitawi1Tara L. Lin2Siddhartha Ganguly3Sunil Abhyankar4Joseph P. McGuirk5Internal Medicine Department, University of Kansas Medical Center, Kansas City, KS 66160, USABlood and Marrow Transplant Program, University of Kansas Medical Center, 2330 Shawnee Mission Pkwy, Westwood, Kansas City, KS 66205, USABlood and Marrow Transplant Program, University of Kansas Medical Center, 2330 Shawnee Mission Pkwy, Westwood, Kansas City, KS 66205, USABlood and Marrow Transplant Program, University of Kansas Medical Center, 2330 Shawnee Mission Pkwy, Westwood, Kansas City, KS 66205, USABlood and Marrow Transplant Program, University of Kansas Medical Center, 2330 Shawnee Mission Pkwy, Westwood, Kansas City, KS 66205, USABlood and Marrow Transplant Program, University of Kansas Medical Center, 2330 Shawnee Mission Pkwy, Westwood, Kansas City, KS 66205, USABendamustine is an alkylating agent currently used in the treatment of lymphoproliferative disorders. Many adverse effects, including a rare case of reversible neurotoxicity, have been reported in association with bendamustine. Herein, we report the first case of irreversible ascending paralysis related to bendamustine.http://dx.doi.org/10.1155/2013/931519
spellingShingle Ashraf Alhafez
Omar S. Aljitawi
Tara L. Lin
Siddhartha Ganguly
Sunil Abhyankar
Joseph P. McGuirk
Bendamustine Associated with Irreversible Ascending Paralysis
Case Reports in Hematology
title Bendamustine Associated with Irreversible Ascending Paralysis
title_full Bendamustine Associated with Irreversible Ascending Paralysis
title_fullStr Bendamustine Associated with Irreversible Ascending Paralysis
title_full_unstemmed Bendamustine Associated with Irreversible Ascending Paralysis
title_short Bendamustine Associated with Irreversible Ascending Paralysis
title_sort bendamustine associated with irreversible ascending paralysis
url http://dx.doi.org/10.1155/2013/931519
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AT omarsaljitawi bendamustineassociatedwithirreversibleascendingparalysis
AT tarallin bendamustineassociatedwithirreversibleascendingparalysis
AT siddharthaganguly bendamustineassociatedwithirreversibleascendingparalysis
AT sunilabhyankar bendamustineassociatedwithirreversibleascendingparalysis
AT josephpmcguirk bendamustineassociatedwithirreversibleascendingparalysis