A Nextflow pipeline for T-cell receptor repertoire reconstruction and analysis from RNA sequencing data

A Nextflow pipeline for T-cell receptor repertoire reconstruction and analysis from RNA sequencing data

T-cell receptor (TCR) analysis is relevant for the study of immune system diseases. The expression of TCRs is usually measured with targeted sequencing approaches where TCR genes are selectively amplified. However, many non-targeted RNA-seq experiments also contain reads of TCR genes, which could be...

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Bibliographic Details
Main Authors: Teresa Rubio, Maria Chernigovskaya, Susanna Marquez, Cristina Marti, Paula Izquierdo-Altarejos, Amparo Urios, Carmina Montoliu, Vicente Felipo, Ana Conesa, Victor Greiff, Sonia Tarazona
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:ImmunoInformatics
Subjects:
T-cell receptor
CD4 isolation
RNA sequencing
Immune repertoire analysis
Minimal Hepatic Encephalopathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119022000040
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