Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans.
Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the modulation of both constitutive and regulated exocytosis. To investigate how TOM-1 regulates exocytosis of synaptic vesicles in vivo, we analyzed C. elegans tom-1 mutants. Our el...
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| Main Authors: | Elena O Gracheva, Anna O Burdina, Andrea M Holgado, Martine Berthelot-Grosjean, Brian D Ackley, Gayla Hadwiger, Michael L Nonet, Robby M Weimer, Janet E Richmond |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-07-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0040261&type=printable |
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