Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.

Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.

Maintenance of physiologic phosphate balance is of crucial biological importance, as it is fundamental to cellular function, energy metabolism, and skeletal mineralization. Fibroblast growth factor-23 (FGF-23) is a master regulator of phosphate homeostasis, but the molecular mechanism of such regula...

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Bibliographic Details
Main Authors: Despina Sitara, Somi Kim, Mohammed S Razzaque, Clemens Bergwitz, Takashi Taguchi, Christiane Schüler, Reinhold G Erben, Beate Lanske
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000154&type=printable
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