Hierarchical metal exposure in umbilical cord blood in relation to oxidative stress and AMPK/NF-κB signaling in preterm membrane rupture

Hierarchical metal exposure in umbilical cord blood in relation to oxidative stress and AMPK/NF-κB signaling in preterm membrane rupture

Abstract To investigate the correlation between metal element levels, AMPK(AMP-activated protein kinase) and NF-κBp65(Nuclear factor kappa-B p65) and PPROM(preterm premature rupture of membranes). 20cases of PPROM,33cases of TPROM(Term premature rupture of membranes), and 33cases of nPROM were selec...

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Bibliographic Details
Main Authors: Siqi Lu, Yikun Zhao, Weibing Chen, Yingying Niu, Dapeng Wang, Zhenai Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Preterm premature rupture of membrane
Metal exposure
Oxidative stress
AMP-activated protein kinase
Nuclear factor-κBp65
Online Access:https://doi.org/10.1038/s41598-025-11374-3
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