Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification

Automated blood cell classification is crucial for hematological analysis, yet the scarcity of annotated medical datasets challenges deep learning models. This study presents a novel semi-supervised Elastic Generative Adversarial Network that enhances classification accuracy, improves synthetic imag...

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Main Authors: Issac Neha Margret, K. Rajakumar
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/10994417/
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author Issac Neha Margret
K. Rajakumar
author_facet Issac Neha Margret
K. Rajakumar
author_sort Issac Neha Margret
collection DOAJ
description Automated blood cell classification is crucial for hematological analysis, yet the scarcity of annotated medical datasets challenges deep learning models. This study presents a novel semi-supervised Elastic Generative Adversarial Network that enhances classification accuracy, improves synthetic image generation quality, and reduces computational complexity. The model utilizes image hallucination, which generates artificial but realistic images to supplement datasets, addressing data imbalance and improving model generalization. The generated images exhibit high fidelity, meaning they closely resemble real blood cell images in texture, morphology, and structural details, ensuring their effectiveness in training deep learning models. Compared to the conventional semi-supervised Wasserstein Generative Adversarial Network, the proposed model achieves a 5.5% increase in classification accuracy, a 34.5% reduction in computational complexity, and a 21.0% decrease in training time, demonstrating superior efficiency and scalability. In addition, it greatly enhances Fréchet Inception Distance and Wasserstein distance, which verifies improved realism and diversity of synthetic samples. Complementing pruning-based optimization ensures reduced model deployment size, rendering it appropriate for real-time medical diagnosis. Through image hallucination, the proposed method sufficiently alleviates data deficiency and improves the reliability of automated blood cell classification, qualifying it as a prospective tool for advanced hematological studies and diagnosis purposes.
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spelling doaj-art-a99cb040a15442adae6c312cdb96ccff2025-08-20T01:53:26ZengIEEEIEEE Access2169-35362025-01-0113848978491010.1109/ACCESS.2025.356853910994417Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and ClassificationIssac Neha Margret0https://orcid.org/0009-0007-2719-7949K. Rajakumar1https://orcid.org/0000-0001-6614-8647School of Computer Science and Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, IndiaSchool of Computer Science and Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, IndiaAutomated blood cell classification is crucial for hematological analysis, yet the scarcity of annotated medical datasets challenges deep learning models. This study presents a novel semi-supervised Elastic Generative Adversarial Network that enhances classification accuracy, improves synthetic image generation quality, and reduces computational complexity. The model utilizes image hallucination, which generates artificial but realistic images to supplement datasets, addressing data imbalance and improving model generalization. The generated images exhibit high fidelity, meaning they closely resemble real blood cell images in texture, morphology, and structural details, ensuring their effectiveness in training deep learning models. Compared to the conventional semi-supervised Wasserstein Generative Adversarial Network, the proposed model achieves a 5.5% increase in classification accuracy, a 34.5% reduction in computational complexity, and a 21.0% decrease in training time, demonstrating superior efficiency and scalability. In addition, it greatly enhances Fréchet Inception Distance and Wasserstein distance, which verifies improved realism and diversity of synthetic samples. Complementing pruning-based optimization ensures reduced model deployment size, rendering it appropriate for real-time medical diagnosis. Through image hallucination, the proposed method sufficiently alleviates data deficiency and improves the reliability of automated blood cell classification, qualifying it as a prospective tool for advanced hematological studies and diagnosis purposes.https://ieeexplore.ieee.org/document/10994417/Blood cell classificationgenerative adversarial network (GAN)image hallucinationmedical image processingperipheral blood smear cellssemi-supervised Wasserstein GAN (SS-WGAN)
spellingShingle Issac Neha Margret
K. Rajakumar
Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
IEEE Access
Blood cell classification
generative adversarial network (GAN)
image hallucination
medical image processing
peripheral blood smear cells
semi-supervised Wasserstein GAN (SS-WGAN)
title Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
title_full Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
title_fullStr Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
title_full_unstemmed Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
title_short Adaptive Elastic GAN for High-Fidelity Blood Cell Image Hallucination and Classification
title_sort adaptive elastic gan for high fidelity blood cell image hallucination and classification
topic Blood cell classification
generative adversarial network (GAN)
image hallucination
medical image processing
peripheral blood smear cells
semi-supervised Wasserstein GAN (SS-WGAN)
url https://ieeexplore.ieee.org/document/10994417/
work_keys_str_mv AT issacnehamargret adaptiveelasticganforhighfidelitybloodcellimagehallucinationandclassification
AT krajakumar adaptiveelasticganforhighfidelitybloodcellimagehallucinationandclassification