Cysteine-rich 61 mediates inflammation by the NF-κB/cyclooxygenase-2 pathway in RF/6A cells

Cysteine-rich 61 mediates inflammation by the NF-κB/cyclooxygenase-2 pathway in RF/6A cells

PURPOSE: Cysteine-rich 61 (Cyr61) may enhance angiogenesis and inflammation in diabetic retinopathy (DR). Cyclooxygenase-2 (COX-2) is an immediate-early gene product of inflammation and it also plays an important role in developing DR. We aim to investigate the effects of Cyr61 on COX-2 expression i...

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Bibliographic Details
Main Authors: Po-Ting Yeh, Jian-Jang You, Chang-Hao Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Taiwan Journal of Ophthalmology
Subjects:
akt
cyclooxygenase-2
cysteine-rich 61
integrin
nf-κb
signal transduction
Online Access:https://journals.lww.com/10.4103/tjo.TJO-D-24-00086
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