Fluconazole Resistance and Heteroresistance in Cryptococcus spp.: Mechanisms and Implications

Fluconazole Resistance and Heteroresistance in Cryptococcus spp.: Mechanisms and Implications

ABSTRACT The reference methodology for evaluating antifungal susceptibility is based on determining the minimum inhibitory concentration (MIC), which is the lowest drug concentration capable of inhibiting fungal growth. However, such MIC data are insufficient to measure antifungal susceptibility if...

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Main Authors: Izabela de Mesquita Bárcia Moreira, Naira Sulany Oliveira de Sousa, Juan Diego Ribeiro de Almeida, Robert Langlady Lira Rosas Filho, Katia Santana Cruz, Ani Beatriz Jackisch Matsuura, Márcia de Souza Carvalho Melhem, Érica Simplício de Souza, Hagen Frickmann, Marcus Vinícius Guimarães Lacerda, João Vicente Braga de Souza
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2025-03-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Cryptococcus spp.
heteroresistance
antifungal
fluconazole
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822025000100200&lng=en&tlng=en
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