Multiple highly methylated CpG sites as potential epigenetic markers for the diagnosis of prostate cancer

Multiple highly methylated CpG sites as potential epigenetic markers for the diagnosis of prostate cancer

Abstract Background Prostate cancer (PCa) remains the leading cause of cancer deaths in men. The prostate-specific antigen (PSA) test is widely used for PCa screening, but it lacks specificity and can lead to over-diagnosis and over-treatment. New, effective and affordable markers are therefore need...

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Bibliographic Details
Main Authors: Jean-Pierre Roperch, Guillaume Charbonnier, Sandy Figiel, Alastair Lamb, Ian Mills, Claude Hennion, Géraldine Cancel-Tassin, Olivier Cussenot
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Clinical Epigenetics
Subjects:
Prostate cancer
Methylome sequencing
Epigenetic DNA markers
Methylation-specific PCR
Online Access:https://doi.org/10.1186/s13148-025-01930-z
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