Association between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification in adults: Insights from the National Health and Nutrition Examination Survey (2013–2014)
Background This cross-sectional study aimed to investigate the association between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification in adults aged ≥40 years in the United States using data from the 2013–2014 National Health and Nutrition Examination Surve...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-08-01
|
| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605251362017 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Background This cross-sectional study aimed to investigate the association between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification in adults aged ≥40 years in the United States using data from the 2013–2014 National Health and Nutrition Examination Survey. Method Multivariable logistic regression and restricted cubic splines models were used to assess the association between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification. Results Among 2665 participants, 800 were diagnosed with abdominal aortic calcification. Multivariable logistic regression analysis revealed a positive association between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification (odds ratio: 1.33; 95% confidence interval: 1.13–1.57), and a nonlinear dose–response relationship was observed. Subgroup analysis suggested that the relationship between the monocyte-to-high-density lipoprotein cholesterol ratio and abdominal aortic calcification was more pronounced in females and nonsmokers. Conclusions The monocyte-to-high-density lipoprotein cholesterol ratio was positively associated with the prevalence of abdominal aortic calcification among individuals aged ≥40 years. A persistently elevated monocyte-to-high-density lipoprotein cholesterol ratio may contribute to an increased burden of abdominal aortic calcification. |
|---|---|
| ISSN: | 1473-2300 |