Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center
Purpose. To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal. Methods. Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected v...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/8848659 |
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| author | Pranav Shrestha Sadhana Sharma Ranju Kharel |
| author_facet | Pranav Shrestha Sadhana Sharma Ranju Kharel |
| author_sort | Pranav Shrestha |
| collection | DOAJ |
| description | Purpose. To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal. Methods. Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected visual acuity, intraocular pressure, and slit lamp examination of anterior and posterior segments. Baseline blood investigations, chest X-ray, fundus photography, and fundus fluorescent angiography (FFA) were performed on all the patients. Results. The mean age at presentation was 46±8.43 years with female predominance (83.3%). The disease was complete in 16.7%, incomplete in 16.7%, and probable in 66.7% of the patients. Most cases presented in acute uveitis stage (66.7%). The most common finding in acute cases was serous retinal detachment (66.7%), followed by disc edema (58.3%), whereas in chronic cases, depigmented fundus was the most common. All cases had bilateral presentation. Conclusion. VKH is an important cause of bilateral loss of vision and has a good visual prognosis if aggressive treatment is initiated during the early stages. |
| format | Article |
| id | doaj-art-a98a4b13d3c540e7a50eb97ba58a27d3 |
| institution | OA Journals |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-a98a4b13d3c540e7a50eb97ba58a27d32025-08-20T02:23:06ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/88486598848659Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye CenterPranav Shrestha0Sadhana Sharma1Ranju Kharel2Mechi Eye Hospital, Jhapa 57200, NepalMechi Eye Hospital, Jhapa 57200, NepalDepartment of Uveitis, B. P. Koirala Lions Center for Ophthalmic Studies (BPKLCOS), Institute of Medicine, Maharajgunj, Kathmandu 44600, NepalPurpose. To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal. Methods. Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected visual acuity, intraocular pressure, and slit lamp examination of anterior and posterior segments. Baseline blood investigations, chest X-ray, fundus photography, and fundus fluorescent angiography (FFA) were performed on all the patients. Results. The mean age at presentation was 46±8.43 years with female predominance (83.3%). The disease was complete in 16.7%, incomplete in 16.7%, and probable in 66.7% of the patients. Most cases presented in acute uveitis stage (66.7%). The most common finding in acute cases was serous retinal detachment (66.7%), followed by disc edema (58.3%), whereas in chronic cases, depigmented fundus was the most common. All cases had bilateral presentation. Conclusion. VKH is an important cause of bilateral loss of vision and has a good visual prognosis if aggressive treatment is initiated during the early stages.http://dx.doi.org/10.1155/2021/8848659 |
| spellingShingle | Pranav Shrestha Sadhana Sharma Ranju Kharel Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center Case Reports in Ophthalmological Medicine |
| title | Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center |
| title_full | Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center |
| title_fullStr | Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center |
| title_full_unstemmed | Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center |
| title_short | Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center |
| title_sort | vogt koyanagi harada disease a case series in a tertiary eye center |
| url | http://dx.doi.org/10.1155/2021/8848659 |
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