The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus

Background. While children were initially thought to have serious contributions to the coronavirus disease 2019 (COVID-19) transmission, recent studies suggest otherwise. However, the possible effect of asymptomatic pediatric spread still has not yet received enough attention. The aim of our...

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Main Authors: Umut Gazi, Murat Sayan, Nedim Çakır, Kaya Süer, İlke Beyitler, Ceyhun Dalkan, Burçin Şanlıdağ, Emrah Ruh, Ayşe Arıkan Sarıoğlu, Tamer Şanlıdağ
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2022-02-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/140
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author Umut Gazi
Murat Sayan
Nedim Çakır
Kaya Süer
İlke Beyitler
Ceyhun Dalkan
Burçin Şanlıdağ
Emrah Ruh
Ayşe Arıkan Sarıoğlu
Tamer Şanlıdağ
author_facet Umut Gazi
Murat Sayan
Nedim Çakır
Kaya Süer
İlke Beyitler
Ceyhun Dalkan
Burçin Şanlıdağ
Emrah Ruh
Ayşe Arıkan Sarıoğlu
Tamer Şanlıdağ
author_sort Umut Gazi
collection DOAJ
description Background. While children were initially thought to have serious contributions to the coronavirus disease 2019 (COVID-19) transmission, recent studies suggest otherwise. However, the possible effect of asymptomatic pediatric spread still has not yet received enough attention. The aim of our study was to estimate asymptomatic infection rates among children in the Turkish Republic of Northern Cyprus, by using pediatric patients admitted to a university hospital without any COVID-19-associated symptoms. Methods. Blood samples collected from 80 pediatric patients with no symptoms and history of COVID-19 infection, who were admitted to a university hospital between September 2020 and January 2021, were included in the retrospective study. Isolated serum samples were tested by Dia.Pro SARS-CoV-2 IgG ELISA assays. Results. The patient group included 40 (50%) male and 40 (50%) female patients. The average age of children was 7.6 ± 4.0 years, with min-max ages ranging from 2 to 15 years. Among the 80 patients tested, only one (1.3%) was detected positive by the Dia.Pro IgG ELISA kit. Conclusions. The asymptomatic seropositivity reported in our study suggests the use of randomly performed serologic tests to monitor SARS-CoV-2 infection among the pediatric population in schools that would contribute to the public health fight against COVID-19.
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publisher Hacettepe University Institute of Child Health
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spelling doaj-art-a988611b0f494f0fb8f8a46efed47abd2025-08-20T02:55:41ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212022-02-0164110.24953/turkjped.2021.1330The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern CyprusUmut Gazi0Murat SayanNedim ÇakırKaya Süer1İlke Beyitler2Ceyhun Dalkan3Burçin Şanlıdağ4Emrah Ruh5Ayşe Arıkan SarıoğluTamer Şanlıdağ6Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Cyprus.Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Near East University, Nicosia, Cyprus.Department of Paediatrics, Near East University, Nicosia, Cyprus.Department of Paediatrics, Near East University, Nicosia, Cyprus.Department of Paediatrics, Near East University, Nicosia, Cyprus.Department of Medical Microbiology and Clinical Microbiology, Near East University, Nicosia, Cyprus.DESAM Research Institute, Near East University, Nicosia, Cyprus. Background. While children were initially thought to have serious contributions to the coronavirus disease 2019 (COVID-19) transmission, recent studies suggest otherwise. However, the possible effect of asymptomatic pediatric spread still has not yet received enough attention. The aim of our study was to estimate asymptomatic infection rates among children in the Turkish Republic of Northern Cyprus, by using pediatric patients admitted to a university hospital without any COVID-19-associated symptoms. Methods. Blood samples collected from 80 pediatric patients with no symptoms and history of COVID-19 infection, who were admitted to a university hospital between September 2020 and January 2021, were included in the retrospective study. Isolated serum samples were tested by Dia.Pro SARS-CoV-2 IgG ELISA assays. Results. The patient group included 40 (50%) male and 40 (50%) female patients. The average age of children was 7.6 ± 4.0 years, with min-max ages ranging from 2 to 15 years. Among the 80 patients tested, only one (1.3%) was detected positive by the Dia.Pro IgG ELISA kit. Conclusions. The asymptomatic seropositivity reported in our study suggests the use of randomly performed serologic tests to monitor SARS-CoV-2 infection among the pediatric population in schools that would contribute to the public health fight against COVID-19. https://turkjpediatr.org/article/view/140IgGSARS-CoV-2childrenserologyseropositivity
spellingShingle Umut Gazi
Murat Sayan
Nedim Çakır
Kaya Süer
İlke Beyitler
Ceyhun Dalkan
Burçin Şanlıdağ
Emrah Ruh
Ayşe Arıkan Sarıoğlu
Tamer Şanlıdağ
The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
The Turkish Journal of Pediatrics
IgG
SARS-CoV-2
children
serology
seropositivity
title The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
title_full The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
title_fullStr The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
title_full_unstemmed The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
title_short The pediatric asymptomatic SARS-CoV-2 IgG seropositivity in the Turkish Republic of Northern Cyprus
title_sort pediatric asymptomatic sars cov 2 igg seropositivity in the turkish republic of northern cyprus
topic IgG
SARS-CoV-2
children
serology
seropositivity
url https://turkjpediatr.org/article/view/140
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